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B型主动脉夹层的管理:急性夹层及慢性夹层急性并发症的治疗

Management of Type B Aortic Dissections: Treatment of Acute Dissections and Acute Complications from Chronic Dissections.

作者信息

Thakkar Dolly, Dake Michael D

机构信息

Department of Cardiothoracic Surgery, Falk Cardiovascular Research Center, Stanford University School of Medicine, Stanford, CA.

Department of Cardiothoracic Surgery, Falk Cardiovascular Research Center, Stanford University School of Medicine, Stanford, CA.

出版信息

Tech Vasc Interv Radiol. 2018 Sep;21(3):124-130. doi: 10.1053/j.tvir.2018.06.001. Epub 2018 Jul 5.

Abstract

Aortic dissection is one of the most catastrophic vascular challenges faced by interventionalists, often misdiagnosed and frequently associated with devastating consequences. Stanford type B aortic dissections affects the descending thoracic aorta without any involvement of the ascending aorta. Dissections associated with refractory pain, rapid aneurysm formation, malperfusion syndromes, rupture, or impending rupture are categorized as complicated and distinct from initially uncomplicated type B dissections without the aforementioned complications. Traditionally, uncomplicated type B dissection is managed medically whereas complicated type B dissection requires intervention to limit mortality. Over the last two decades, thoracic endovascular aortic repair (TEVAR) has emerged as an alternative to open surgical repair for treatment of complicated type B dissection. Various societal guidelines now unanimously propose TEVAR as the treatment of choice for management of complicated disease based on its relatively low morbidity and mortality compared to open surgical outcomes. As the consensually acknowledged standard of care for management of patients with complicated lesions, TEVAR is currently being considered for select patients with initially uncomplicated dissection to mitigate the risks of mid and late-term disease progression and aortic-related mortality. This article describes the decision-making treatment algorithm for management of type B aortic dissection. It also provides a comprehensive review of the indications and procedural recommendations for performing TEVAR based on current evidence in the literature. Additionally, the article guides the readers through step-by-step practical considerations, from choosing the optimal graft to insuring its ideal deployment in type B dissection, as well as providing advice on how to handle a variety of procedure-related complications.

摘要

主动脉夹层是介入医生面临的最具灾难性的血管挑战之一,常常被误诊,且往往伴有毁灭性后果。斯坦福B型主动脉夹层累及胸降主动脉,不累及升主动脉。与难治性疼痛、快速形成动脉瘤、灌注不良综合征、破裂或即将破裂相关的夹层被归类为复杂性夹层,与最初无上述并发症的非复杂性B型夹层不同。传统上,非复杂性B型夹层采用内科治疗,而复杂性B型夹层需要进行干预以降低死亡率。在过去二十年中,胸主动脉腔内修复术(TEVAR)已成为治疗复杂性B型夹层的一种替代开放手术修复的方法。基于与开放手术相比相对较低的发病率和死亡率,各种社会指南现在一致推荐TEVAR作为治疗复杂性疾病的首选方法。作为公认的复杂性病变患者治疗的标准护理方法,目前正在考虑为部分最初非复杂性夹层患者进行TEVAR,以降低中期和后期疾病进展及主动脉相关死亡率的风险。本文描述了B型主动脉夹层治疗的决策算法。它还根据文献中的现有证据,对进行TEVAR的适应症和手术建议进行了全面综述。此外,本文还逐步引导读者进行实际考量,从选择最佳移植物到确保其在B型夹层中的理想植入,以及就如何处理各种与手术相关的并发症提供建议。

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