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体外膜肺氧合支持复杂高风险择期经皮冠状动脉介入治疗的结果:单中心经验及文献综述

Outcomes of Extracorporeal Membrane Oxygenation Support for Complex High-Risk Elective Percutaneous Coronary Interventions: A Single-Center Experience and Review of the Literature.

作者信息

Shaukat Arslan, Hryniewicz-Czeneszew Katarzyna, Sun Benjamin, Mudy Karol, Wilson Kelly, Tajti Peter, Stanberry Larissa, Garberich Ross, Sandoval Yader, Burke M Nicholas, Chavez Ivan, Gössl Mario, Henry Timothy, Lips Daniel, Mooney Michael, Poulose Anil, Sorajja Paul, Traverse Jay, Wang Yale, Bradley Steven, Brilakis Emmanouil S

机构信息

Minneapolis Heart Institute, 920 E. 28th Street #300, Minneapolis, MN 55407 USA.

出版信息

J Invasive Cardiol. 2018 Dec;30(12):456-460.

Abstract

OBJECTIVES

Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is most commonly used in patients with cardiac arrest and cardiogenic shock. There are limited data on the use of VA-ECMO for elective, high-risk percutaneous coronary intervention (PCI). We examined the in-hospital and mid-term clinical outcomes in patients undergoing complex, high-risk PCI with VA-ECMO support.

METHODS

. We conducted a retrospective review of ECMO-supported elective high-risk PCIs performed at our institution between May 2012 and May 2017. The electronic medical records and angiograms were individually reviewed. We assessed the in-hospital and mid-term major adverse cardiovascular and cerebrovascular event (MACCE) rates, and reviewed bleeding and vascular complications.

RESULTS

Five patients underwent elective high-risk PCI with ECMO support. Mean age was 66.8 ± 8.6 years and all patients were men. The mean ejection fraction was 26.6 ± 18.0%. Most procedures were unprotected left main PCIs. All PCIs were successful; 1 patient required femoral artery surgical repair. The mean hospital stay post procedure was 6.4 ± 2.0 days. ECMO was successfully weaned in all cases, and the duration of ECMO was <24 hours in 4 cases. There was no occurrence of in-hospital and 1-year MACCE.

CONCLUSION

ECMO can be successfully used for hemodynamic support during elective high-risk PCI.

摘要

目的

静脉-动脉体外膜肺氧合(VA-ECMO)最常用于心脏骤停和心源性休克患者。关于VA-ECMO用于择期、高危经皮冠状动脉介入治疗(PCI)的数据有限。我们研究了在VA-ECMO支持下接受复杂、高危PCI患者的院内及中期临床结局。

方法

我们对2012年5月至2017年5月在我院进行的ECMO支持的择期高危PCI进行了回顾性研究。对电子病历和血管造影进行了单独审查。我们评估了院内及中期主要不良心血管和脑血管事件(MACCE)发生率,并审查了出血和血管并发症。

结果

5例患者在ECMO支持下接受了择期高危PCI。平均年龄为66.8±8.6岁,所有患者均为男性。平均射血分数为26.6±18.0%。大多数手术为无保护左主干PCI。所有PCI均成功;1例患者需要进行股动脉手术修复。术后平均住院时间为6.4±2.0天。所有病例ECMO均成功撤机,4例患者ECMO持续时间<24小时。未发生院内及1年MACCE。

结论

ECMO可成功用于择期高危PCI期间的血流动力学支持。

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