胸壁/乳房加Ⅲ-Ⅳ级淋巴结螺旋断层放疗后的皮肤毒性
Skin toxicity after chest wall/breast plus level III-IV lymph nodes treatment with helical tomotherapy.
作者信息
Lancellotta Valentina, Chierchini Sara, Perrucci Elisabetta, Saldi Simonetta, Falcinelli Lorenzo, Iacco Martina, Zucchetti Claudio, Palumbo Isabella, Bini Vittorio, Aristei Cynthia
机构信息
a Radiation Oncology Section , Department of Surgical and Biomedical Sciences , University of Perugia and Perugia General Hospital , Italy.
b Radiation Oncology Section University of Perugia , Italy.
出版信息
Cancer Invest. 2018;36(9-10):504-511. doi: 10.1080/07357907.2018.1545854. Epub 2018 Dec 5.
INTRODUCTION
To evaluate the incidence of toxicity in breast cancer with helical tomotherapy (HT).
MATERIALS AND METHODS
51 patients with breast cancer were assigned to postoperative radiotherapy by means of HT to the chest wall/breast plus draining nodes. During HT treatment, toxicity was monitored and were assessed using the Common Terminology Criteria for Adverse Events 4.0 scale.
RESULTS
Acute skin G3 toxicity observed in 1.9% cases. No acute or late G4 toxicity was observed. At a median follow-up of 21 months 2 patients have late G1 toxicity.
CONCLUSIONS
HT was associated with a low incidence of low-grade skin toxicity.
引言
评估螺旋断层放射治疗（HT）在乳腺癌治疗中的毒性发生率。
材料与方法
51例乳腺癌患者通过HT接受胸壁/乳房加引流淋巴结的术后放疗。在HT治疗期间，监测毒性反应，并使用不良事件通用术语标准4.0量表进行评估。
结果
1.9%的病例观察到急性皮肤3级毒性。未观察到急性或晚期4级毒性。在中位随访21个月时，2例患者出现晚期1级毒性。
结论
HT与低级别皮肤毒性的低发生率相关。
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