Department of Obstetrics and Gynaecology, Groote Schuur Hospital and Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; African Network and Registry for Assisted Reproductive Technology.
Department of Obstetrics and Gynaecology, Groote Schuur Hospital and Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; African Network and Registry for Assisted Reproductive Technology.
Reprod Biomed Online. 2019 Feb;38(2):216-224. doi: 10.1016/j.rbmo.2018.11.001. Epub 2018 Nov 22.
What were utilization, outcomes and practices in assisted reproductive technology (ART) in Africa in 2013?
To initiate a data registry in Africa, retrospective summary data were collected in a cross-sectional survey.
Forty ART centres from 13 countries collectively reported 25,770 initiated cycles. Regional ART utilization could not be established due to large inter-country variations and insufficient data. The pregnancy rate per aspiration for fresh non-donor IVF and intracytoplasmic sperm injection was 28.0% and 35.8%, with a preponderance of women under 35 years (57.3%). Deliveries were reported for only 56.1% of pregnancies; the remainder were lost to follow-up. A mean of 2.41 embryos were transferred. The multiple delivery rate was 26.7% (25.5% twins and 1.2% triplets). Most twins (52.7%) and triplets (73.7%) were born pre-term. Oocyte donation represented 7% of all fresh and frozen transfers.
This marks the beginning of an ART registry in Africa, Since ART utilization could not be established, the degree of access to ART remains speculative. Pregnancy rates were favourable but underpinned by a preponderance of young women and the transfer of multiple embryos. Efforts are needed to explore treatment barriers, improve pregnancy follow-up and reduce the high rate of multiples. This inaugural report from the African Network and Registry for Assisted Reproductive Technology (ANARA) indicates a willingness and ability of ART centres to voluntarily report and monitor utilization and outcomes of ART, which reflects a rising standard of ART in Africa. It is anticipated that more centres and countries will join ANARA to continue this trend.
2013 年非洲辅助生殖技术（ART）的利用情况、结局和实践如何？
为在非洲建立一个数据登记处，我们进行了一项横断面调查，回顾性地汇总了数据。
来自 13 个国家的 40 个 ART 中心共报告了 25770 个启动周期。由于各国之间差异很大且数据不足，无法确定区域内的 ART 利用率。新鲜非捐赠 IVF 和胞浆内精子注射的每抽吸妊娠率分别为 28.0%和 35.8%，其中 57.3%的患者年龄在 35 岁以下。只有 56.1%的妊娠报告了分娩；其余的因失访而无法获得结局。平均转移了 2.41 个胚胎。多胎分娩率为 26.7%（25.5%为双胞胎，1.2%为三胞胎）。大多数双胞胎（52.7%）和三胞胎（73.7%）早产。卵母细胞捐赠占所有新鲜和冷冻移植的 7%。
这标志着非洲辅助生殖技术登记处的建立。由于无法确定 ART 的利用情况，获得 ART 的程度仍存在推测。妊娠率是有利的，但主要是由于年轻妇女和移植多个胚胎。需要努力探讨治疗障碍，改善妊娠随访，并降低多胎妊娠的发生率。非洲生殖网络和辅助生殖技术登记处（ANARA）的这份首份报告表明，ART 中心有意愿和能力自愿报告和监测 ART 的利用情况和结局，这反映了非洲 ART 水平的提高。预计将有更多的中心和国家加入 ANARA 以延续这一趋势。
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