Colin Marius, Klingelschmitt Flora, Charpentier Emilie, Josse Jérôme, Kanagaratnam Lukshe, De Champs Christophe, Gangloff Sophie C
Biomatériaux et Inflammation en Site Osseux, EA 4691, SFR CAP-Santé, UFR de Pharmacie, Université de Reims Champagne Ardenne, 51100 Reims, France.
Service de Microbiologie, UFR pharmacie, Université de Reims Champagne-Ardenne, 51100 Reims, France.
Materials (Basel). 2018 Dec 6;11(12):2479. doi: 10.3390/ma11122479.
In the healthcare environment, microorganisms' cross-transmission between inanimate surfaces and patients or healthcare workers can lead to healthcare-associated infections. A recent interest has grown to create antimicrobial copper touch surfaces, in order to counteract microbial spread in the healthcare environment. For the first time, five French long-term care facilities were at 50% fitted with copper alloys door handles and handrails. Related to the environmental bacterial contamination, 1400 samples were carried out on copper and control surfaces over three years after copper installation. In addition, some copper door handles were taken from the different facilities, and their specific activity against methicillin-resistant (MRSA) was tested in vitro. In comparison to control surfaces, copper door handles and handrails revealed significantly lower contamination levels. This difference was observed in the five long-term care facilities and it persists through the three years of the study. High and extreme levels of bacterial contamination were less frequent on copper surfaces. Although, the antibacterial activity of copper surfaces against MRSA was lowered after three years of regular use, it was still significant as compared to inert control surfaces. Therefore, copper containing surfaces are promising actors in the non-spreading of environmental bacterial contamination in healthcare facilities.
在医疗环境中,微生物在无生命表面与患者或医护人员之间的交叉传播会导致医疗相关感染。最近,人们越来越关注创建抗菌铜接触表面,以对抗医疗环境中的微生物传播。首次有五家法国长期护理机构50%的门把和扶手安装了铜合金。在安装铜制品后的三年里,针对环境细菌污染,在铜表面和对照表面上进行了1400次采样。此外,从不同机构获取了一些铜门把手,并在体外测试了它们对耐甲氧西林金黄色葡萄球菌(MRSA)的特定活性。与对照表面相比,铜门把手和扶手的污染水平显著降低。在这五家长期护理机构中均观察到了这种差异,并且在三年的研究期间一直存在。铜表面上细菌污染的高水平和极端水平出现的频率较低。虽然,经过三年的常规使用后,铜表面对MRSA的抗菌活性有所降低,但与惰性对照表面相比,仍然显著。因此,含铜表面有望在医疗设施中防止环境细菌污染传播方面发挥作用。