Olarinoye-Akorede Sefiya Adebanke, Farouk Bilkisu, Liman Almustapha Aliyu, Kajogbola Gbenga Abimbola
Radiology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
Radiology, Barau Dikko Teaching Hospital Kaduna, Kaduna, Nigeria.
BMJ Case Rep. 2018 Dec 14;11(1):e225993. doi: 10.1136/bcr-2018-225993.
Juvenile papillomatosis is a benign epithelial proliferative tumour of young women. It was recognised as a distinct clinicopathological entity with defining criteria by Rosen since 1980. However, giant juvenile papillomatosis is rare. We report a case of a 14-year-old girl who presented to our institution's breast clinic with a huge right breast mass measuring 20 cm × 15 cm. She had no personal history of previous breast disease and there was no family history of breast cancer. Our initial preoperative diagnosis was of a phylloides tumour. The patient had a total excision of her breast mass which revealed florid juvenile papillomatosis at histology. This presentation highlights the clinical presentation and imaging features of juvenile papillomatosis. The classical histopathological characteristics, unusual microscopic findings and management of a huge-sized tumour in an adolescent Nigerian patient are also presented.
青少年乳头状瘤病是年轻女性的一种良性上皮增生性肿瘤。自1980年以来,罗森将其认定为一种具有明确诊断标准的独特临床病理实体。然而,巨大型青少年乳头状瘤病较为罕见。我们报告一例14岁女孩,她因右乳有一个20厘米×15厘米的巨大肿块而就诊于我院乳腺科。她既往无乳腺疾病个人史,也无乳腺癌家族史。我们最初的术前诊断为叶状肿瘤。患者接受了乳腺肿块全切术,组织学检查显示为活跃的青少年乳头状瘤病。本病例展示了青少年乳头状瘤病的临床表现及影像学特征。文中还介绍了一名尼日利亚青少年患者巨大肿瘤的经典组织病理学特征、不寻常的显微镜下表现及治疗情况。