Spyropoulos Alex C, Myrka Anne, Triller Darren M, Ragan Stephen, York Collin, King Jaz-Michael, Lee Ti-Kuang
Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, NY, United States.
IPRO, Albany, NY, United States.
JMIR Mhealth Uhealth. 2018 Dec 21;6(12):e11090. doi: 10.2196/11090.
Anticoagulants are major contributors to preventable adverse drug events, and their optimal management in the periprocedural period is particularly challenging. Traditional methods of disseminating clinical guidelines and tools cannot keep pace with the rapid expansion of available therapeutic agents, approved indications for use, and published medical evidence, so a mobile app, Management of Anticoagulation in the Periprocedural Period (MAPPP), was developed and disseminated to provide clinicians with guidance that reflects the most current medical evidence.
The objective of this study was to assess the global, national, and state-level acquisition of a mobile app since its initial release and characterize individual episodes of use based on drug selection, procedural bleeding risk, and patient thromboembolic risk.
Data were extracted from a mobile app usage tracker (Google Analytics) to characterize new users and completed episodes temporally (by calendar quarter) and geographically (globally, nationally, and in the targeted US state of New York) for the period between April 1, 2016 and September 30, 2017.
The app was acquired by 2866 new users in the measurement period, and the users completed nearly 10,000 individual episodes of use. Acquisition and utilization spanned 51 countries globally, predominantly in the United States and particularly in New York State. Warfarin and rivaroxaban were the most frequently selected drugs, and completed episodes most frequently included the selection of high bleeding risk (4888/9963, 49.06%) and high thromboembolic risk categories (4500/9963, 45.17%).
The MAPPP app is a successful means of disseminating current guidance on periprocedural anticoagulant use, as indicated by broad global uptake and upward trends in utilization. Limitations in access to provider and patient-specific data preclude objective evaluation of the clinical impact of the app. An ongoing study incorporating app logic into electronic health record systems at participant health systems will provide a more definitive evaluation of the clinical impact of the app logic.
抗凝剂是可预防药物不良事件的主要促成因素,其在围手术期的最佳管理尤其具有挑战性。传播临床指南和工具的传统方法无法跟上可用治疗药物、批准的使用适应症以及已发表医学证据的快速增长,因此开发并推广了一款移动应用程序“围手术期抗凝管理(MAPPP)”,为临床医生提供反映最新医学证据的指导。
本研究的目的是评估一款移动应用程序自首次发布以来在全球、国家和州层面的获取情况,并根据药物选择、手术出血风险和患者血栓栓塞风险来描述个体使用情况。
从移动应用程序使用跟踪器(谷歌分析)中提取数据,以按时间(按日历季度)和地理位置(全球、国家以及美国目标州纽约)描述2016年4月1日至2017年9月30日期间的新用户和完整使用情况。
在测量期间,该应用程序有2866名新用户获取,用户完成了近10000次个体使用。获取和使用范围覆盖全球51个国家,主要在美国,尤其是纽约州。华法林和利伐沙班是最常被选择的药物,完整使用情况中最常包括选择高出血风险(4888/9963,49.06%)和高血栓栓塞风险类别(4500/9963,45.17%)。
MAPPP应用程序是传播围手术期抗凝剂使用当前指导的成功手段,全球广泛采用和使用呈上升趋势表明了这一点。获取提供者和患者特定数据的局限性妨碍了对该应用程序临床影响的客观评估。一项正在进行的将应用程序逻辑纳入参与健康系统的电子健康记录系统的研究将对应用程序逻辑的临床影响提供更明确的评估。