Division of Vascular Surgery, Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pa.
Division of Vascular Surgery, Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pa.
J Vasc Surg. 2019 Jun;69(6):1766-1775. doi: 10.1016/j.jvs.2018.09.049. Epub 2018 Dec 21.
Open procedures are often required for late complications after endovascular aneurysm repair (EVAR). Our aim was to describe the indications for open interventions and their postoperative outcomes and to specifically examine our experience with limited conversions in which problem endoleaks are targeted without endograft explantation.
We reviewed patients from 2002 to 2017 who underwent any surgical abdominal aortic operation after a previous EVAR. Baseline characteristics, preoperative imaging, procedural details, and postoperative outcomes were reviewed. The primary end point was 30-day mortality.
There were 102 patients who underwent open conversion 3.8 ± 3.1 years after EVAR. The numbers increased significantly in recent years, with 18 cases performed in 2016; 48.5% of patients had undergone 1.9 ± 1.0 prior endovascular interventions. The indication for surgical conversion was an endoleak in 85 patients and infection in 15. One patient had a limb occlusion and another a proximal aneurysm. The 30-day mortality was 6.2% in 65 patients treated electively for endoleak but higher in 20 ruptures (40.0%) and 15 infections (40.0%). In a multivariate logistic regression model, independent predictors of 30-day mortality were rupture (odds ratio [OR], 6.70; 95% confidence interval [CI], 1.75-25.60; P = .005), endograft infection (OR, 8.48; 95% CI, 1.99-36.20; P = .004), and use of a supraceliac clamp (OR, 4.80; 95% CI, 1.47-15.66; P = .009). Transient acute kidney injury (12.8%) and prolonged intubation (11.8%) were the most common postoperative complications. In 65 patients treated for endoleak without rupture, 37 underwent endograft explantation, whereas 28 had a graft-preserving intervention (branch vessel ligation for type II endoleak in 26, external banding of the aneurysm neck for type IA endoleak in 8). Mortality was 8.1% when the endograft was explanted and 3.6% when it was not (P = .63). During 3.0 ± 3.5 years of follow-up, there was one reintervention after endograft explantation (for rupture secondary to type IB endoleak) and two reinterventions after graft preservation (for a new type IA endoleak and a new type II endoleak). Survival was 87.4% at 1 year and 70.9% at 5 years.
Open conversion is playing an increasing role in the management of late EVAR complications. Endoleaks treated electively by open conversion are reasonably safe and show good midterm durability, even with graft-preserving interventions that avoid endograft explantation.
血管内动脉瘤修复(EVAR)后发生晚期并发症时通常需要进行开放手术。我们的目的是描述开放干预的适应证及其术后结果,并特别研究我们在有限的转换中的经验,即针对没有移植物取出的问题内漏进行靶向治疗。
我们回顾了 2002 年至 2017 年间,在之前的 EVAR 后接受任何腹部主动脉手术的患者。回顾了基线特征、术前影像学、手术细节和术后结果。主要终点是 30 天死亡率。
102 例患者在 EVAR 后 3.8±3.1 年进行了开放转换。近年来,这一数字显著增加,2016 年有 18 例;48.5%的患者曾进行过 1.9±1.0 次血管内干预。手术转换的指征是 85 例患者存在内漏,15 例患者存在感染。1 例患者出现肢体闭塞,另 1 例患者出现近端动脉瘤。65 例因内漏选择性接受治疗的患者 30 天死亡率为 6.2%,但 20 例破裂(40.0%)和 15 例感染(40.0%)患者的死亡率较高。在多变量逻辑回归模型中,30 天死亡率的独立预测因素为破裂(比值比[OR],6.70;95%置信区间[CI],1.75-25.60;P=0.005)、移植物感染(OR,8.48;95%CI,1.99-36.20;P=0.004)和使用腹主动脉夹(OR,4.80;95%CI,1.47-15.66;P=0.009)。短暂性急性肾损伤(12.8%)和长时间插管(11.8%)是最常见的术后并发症。在 65 例无破裂的内漏患者中,37 例行移植物取出,28 例行保留移植物的干预(26 例行 II 型内漏分支血管结扎,8 例行 I 型内漏瘤颈外带)。移植物取出的死亡率为 8.1%,不移植物取出的死亡率为 3.6%(P=0.63)。在 3.0±3.5 年的随访期间,移植物取出后有 1 例再干预(继发于 IB 型内漏的破裂),保留移植物后有 2 例再干预(新发 IA 型内漏和新发 II 型内漏)。1 年生存率为 87.4%,5 年生存率为 70.9%。
开放转换在 EVAR 晚期并发症的管理中发挥着越来越重要的作用。通过开放转换选择性治疗的内漏是相当安全的,甚至在避免移植物取出的保留移植物的干预下,也显示出良好的中期耐久性。