1 Department of Urology, Guy's and St Thomas' Hospitals, London, United Kingdom.
2 Department of Urology, Derriford Hospital, Plymouth, United Kingdom.
J Endourol. 2019 Mar;33(3):242-247. doi: 10.1089/end.2018.0610. Epub 2019 Feb 1.
To present our experience of the Detour extra-anatomic stent (EAS; Porges-Coloplast, Denmark) to bypass ureteric obstruction. Use of the EAS is indicated in patients with complex ureteric strictures or malignant disease, where long-term nephrostomy drainage is undesirable.
Between December 2001 and October 2017, 20 Detour EAS were implanted into 13 patients. The primary indication was ureteric obstruction or injury secondary to metastatic malignancy, or from treatment for malignancy. Five patients required bilateral EAS, with two patients having bilateral EAS following initial unilateral insertion. In 11 patients, the stent was inserted into their bladder, with 2 diverted into a double-barreled stoma. The mean age at the time of implantation was 64 years (range: 50-83 years), and the median follow-up was 12 months (range: 1.5-42 months).
Four patients required stent revision for urinary leaks, and two developed recurrent urinary tract infections in their stent requiring intravenous antibiotics. All EAS continued to drain successfully following treatment or revision. One patient died due to complications from dislodgement of the stent, leading to laparotomy and intra-abdominal sepsis. Seven patients died due to progression of metastatic malignant disease, and the Detour EAS was functioning in all seven at time of death. The remaining five patients are well with functioning Detour EAS.
The Detour EAS system provides a suitable alternative option for urinary diversion, affording a good quality of life to carefully selected patients with multiple comorbidities and malignant disease.
介绍我们使用 Detour 外生型支架(EAS;丹麦 Porges-Coloplast)治疗输尿管梗阻的经验。EAS 适用于存在复杂输尿管狭窄或恶性疾病、需要长期肾造瘘引流的患者。
2001 年 12 月至 2017 年 10 月,我们对 13 名患者共植入 20 枚 Detour EAS。主要适应证为转移性恶性肿瘤或恶性肿瘤治疗所致的输尿管梗阻或损伤。5 名患者需要双侧 EAS,其中 2 名患者在首次单侧插入后双侧插入 EAS。11 名患者将支架插入膀胱,2 名患者将支架插入双腔造口。植入时的平均年龄为 64 岁(范围:50-83 岁),中位随访时间为 12 个月(范围:1.5-42 个月)。
4 名患者因尿漏需要支架修正,2 名患者因支架内复发性尿路感染需要静脉使用抗生素。所有 EAS 在治疗或修正后均继续成功引流。1 名患者因支架移位导致并发症死亡,行剖腹术和腹腔内感染。7 名患者因转移性恶性肿瘤进展而死亡,死亡时 Detour EAS 仍在发挥作用。其余 5 名患者情况良好,Detour EAS 功能正常。
Detour EAS 系统为尿流改道提供了一种合适的替代选择,为患有多种合并症和恶性疾病的精选患者提供了良好的生活质量。