Karabuk University Faculty of Medicine, Department of Cardiology, Karabuk, Turkey.
Karabuk University Faculty of Medicine, Department of Cardiology, Karabuk, Turkey.
Heart Lung. 2019 Sep-Oct;48(5):446-451. doi: 10.1016/j.hrtlng.2018.12.001. Epub 2018 Dec 28.
Cardiovascular events after orthopedic surgery may result in mortality. Therefore, predictors of early cardiovascular events after elective orthopedic surgery are required.
The aim of this study is to investigate the relationship between aortic arch calcification and 30-day major adverse cardiac events following elective orthopedic surgery.
Patients who had undergone orthopedic surgery were screened. Preoperative detailed anamnesis was taken. Echocardiography and standard chest x-ray were performed.Patients were followed in terms of perioperative 30-days major cardiac events and were classified into two groups according to development of perioperative major adverse cardiac events.Aortic arch calcification was evaluated by two cardiologists, blinded to study findings and was graded as 0 to 3 on chest x-ray.
A total of 1060 patients were approached for the study participation. Of these 714 were included in the study (mean age: 70.43, 65% female). Cardiovascular events occurred in 33 patients. As compared to the patients without cardiac events, the prevalence of aortic arch calcification, coronary artery disease, hypertension, and smoking were higher in patients with cardiac events. In addition, Lee index, left ventricular end-systolic, end-diastolic and left atrial diameter were significantly higher, GFR values were significantly lower in the group with cardiac events.Multivariate regression analysis showed that smoking (OR 5.031, 95% CI 1.602 to 15.794), presence of hypertension (OR 5.133, 95% CI 1.297 to 20.308) and aortic arch calcification (OR 6.920, 95% CI 3.890 to 12.310) are independent predictors of major cardiac events within 30-day of elective orthopedic surgery.
Presence of aortic arch calcification is associated with development of major cardiac events within 30-days after elective orthopedic surgery.
骨科手术后的心血管事件可导致死亡。因此,需要预测择期骨科手术后早期心血管事件的预测因素。
本研究旨在探讨主动脉弓钙化与择期骨科手术后 30 天主要不良心脏事件的关系。
筛选接受骨科手术的患者。进行术前详细病史询问。进行超声心动图和标准胸部 X 线检查。根据围手术期 30 天主要心脏事件的发生情况对患者进行随访,并根据围手术期主要不良心脏事件的发生情况将患者分为两组。由两名对研究结果不知情的心脏病专家评估主动脉弓钙化,并在胸部 X 线上对其进行 0 至 3 级评分。
共有 1060 名患者被邀请参加研究。其中 714 名患者被纳入研究(平均年龄:70.43 岁,65%为女性)。33 名患者发生心血管事件。与无心脏事件的患者相比,发生心脏事件的患者中主动脉弓钙化、冠心病、高血压和吸烟的患病率更高。此外,心脏事件组的 Lee 指数、左心室收缩末期、舒张末期和左心房直径明显更高,GFR 值明显更低。多变量回归分析显示,吸烟(OR 5.031,95%CI 1.602 至 15.794)、高血压(OR 5.133,95%CI 1.297 至 20.308)和主动脉弓钙化(OR 6.920,95%CI 3.890 至 12.310)是择期骨科手术后 30 天内发生主要心脏事件的独立预测因素。
主动脉弓钙化与择期骨科手术后 30 天内发生主要心脏事件有关。