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银纳米颗粒、氧化锌纳米颗粒和二氧化钛纳米颗粒对牙釉质和牙本质微剪切粘结强度的影响。

Effect of Silver Nanoparticles, Zinc Oxide Nanoparticles and Titanium Dioxide Nanoparticles on Microshear Bond Strength to Enamel and Dentin.

作者信息

Jowkar Zahra, Farpour Nazbanoo, Koohpeima Fatemeh, Mokhtari Mohammad J, Shafiei Fereshteh

机构信息

Department of Operative Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran, Phone: +98-71-36263193, e-mail:

Department of Operative Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.

出版信息

J Contemp Dent Pract. 2018 Nov 1;19(11):1404-1411.

Abstract

AIM

This study was aimed to evaluate whether antibacterial pretreatment of enamel and dentin with silver nanoparticles (SNPs), zinc oxide nanoparticles (ZNPs) and titanium dioxide nanoparticles (TNPs) has any effect on the microshear bond strength of an etch-and-rinse adhesive system.

MATERIALS AND METHODS

Eighty human third molars were randomly assigned to eight subgroups (n = 10). Enamel groups included no pretreatment (E), pretreatments with SNPs (ESNP), ZNPs (EZNP) and TNPs (ETNP) before acid etching and adhesive application. Dentinal groups included no pretreat-ment (D), pretreatments with SNPs (DSNP), ZNPs (DZNP) and TNPs (DTNP). The specimens were bonded by Adper Single Bond and polyvinyl chloride microtubes and were restored with Z250 composite. The bonded surfaces underwent microshear bond strength (uSBS) test. Data in megapascal (MPa) were analyzed with the Kruskal-Wallis test and the Mann-Whitney test (p = 0.05).

RESULTS

There was not a significant difference among the groups in enamel (p > 0.05). There was no significant difference between the application of three nanoparticles and the control group in dentin. However, DSNPs had a higher uSBS (25.60 ± 14.61) than that of the DZNPs and DTNPs groups (p = 0.03 and p = 0.001, respectively). Also, the mean uSBS value was lower in dentin groups compared to the respective enamel groups (p < 0.05) except for groups DSNPs and ESNPs in which no significant difference was found (p > 0.05).

CONCLUSION

Pretreatment with SNPs, TNPs, and ZNPs can be suggested to achieve potent antibacterial activities without compromising the bond strength. The best result was obtained for pretreatment with SNPs compared to pretreatment with TNPs or ZNPs in dentin and enamel, albeit the differences were not significant in the enamel groups.

CLINICAL SIGNIFICANCE

Effective antibacterial treatment prior to adhesive bonding application is desirable to provide successful restoration if it would not adversely affect the bond strength of the adhesive system. Nanoparticles can be applied to meet this goal.

摘要

目的

本研究旨在评估用银纳米颗粒(SNPs)、氧化锌纳米颗粒(ZNPs)和二氧化钛纳米颗粒(TNPs)对牙釉质和牙本质进行抗菌预处理是否会对酸蚀冲洗粘结系统的微剪切粘结强度产生影响。

材料与方法

80颗人第三磨牙随机分为8个亚组(n = 10)。牙釉质组包括酸蚀和粘结剂应用前不进行预处理(E)、用SNPs预处理(ESNP)、用ZNPs预处理(EZNP)和用TNPs预处理(ETNP)。牙本质组包括不进行预处理(D)、用SNPs预处理(DSNP)、用ZNPs预处理(DZNP)和用TNPs预处理(DTNP)。样本用Adper Single Bond粘结剂和聚氯乙烯微管进行粘结,并用Z250复合树脂修复。对粘结表面进行微剪切粘结强度(uSBS)测试。以兆帕(MPa)为单位的数据用Kruskal-Wallis检验和Mann-Whitney检验进行分析(p = 0.05)。

结果

牙釉质组各亚组之间无显著差异(p > 0.05)。在牙本质中,三种纳米颗粒的应用与对照组之间无显著差异。然而,DSNPs组的uSBS(25.60 ± 14.61)高于DZNPs组和DTNPs组(分别为p = 0.03和p = 0.001)。此外,除DSNPs组和ESNPs组未发现显著差异(p > 0.05)外,牙本质组的平均uSBS值低于相应的牙釉质组(p < 0.05)。

结论

可以建议用SNPs、TNPs和ZNPs进行预处理,以在不影响粘结强度的情况下实现有效的抗菌活性。与在牙本质和牙釉质中用TNPs或ZNPs预处理相比,用SNPs预处理获得了最佳结果,尽管牙釉质组中的差异不显著。

临床意义

如果不会对粘结系统的粘结强度产生不利影响,那么在粘结剂粘结应用前进行有效的抗菌治疗对于实现成功修复是可取的。纳米颗粒可用于实现这一目标。

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