Institute of Vertebrate Biology, Czech Academy of Sciences, Brno, Czech Republic.
Elife. 2019 Jan 8;8:e41548. doi: 10.7554/eLife.41548.
The turquoise killifish, , is a promising vertebrate model in ageing research and an emerging model organism in genomics, regenerative medicine, developmental biology and ecotoxicology. Its lifestyle is adapted to the ephemeral nature of shallow pools on the African savannah. Its rapid and short active life commences when rains fill the pool: fish hatch, grow rapidly and mature in as few as two weeks, and then reproduce daily until the pool dries out. Its embryos then become inactive, encased in the dry sediment and protected from the harsh environment until the rains return. This invertebrate-like life cycle (short active phase and long developmental arrest) combined with a vertebrate body plan provide the ideal attributes for a laboratory animal.
蓝胸丽鱼， ，是衰老研究中极有前途的脊椎动物模型，也是基因组学、再生医学、发育生物学和生态毒理学中的新兴模式生物。它的生活方式适应于非洲稀树草原上短暂存在的浅水池。当雨水充满水池时，它的快速而短暂的活跃生活就开始了：鱼孵化，迅速生长并在短短两周内成熟，然后每天繁殖，直到水池干涸。然后，它们的胚胎进入休眠状态，被包裹在干燥的沉积物中，并受到保护，免受恶劣环境的影响，直到雨水再次降临。这种类似无脊椎动物的生命周期（短暂的活跃期和长期的发育停滞）与脊椎动物的身体结构相结合，为实验室动物提供了理想的特征。
