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0.2%生物黏附性氯己定凝胶在降低干槽症发生率中的作用

Role Of 0.2% Bio-Adhesive Chlorhexidine Gel In Reducing Incidence Of Alveolar Osteitis.

作者信息

Shad Samia, Hussain Syed Majid, Tahir Muhammad Waheed, Rahat Geelani Syeda Rabia, Khan Saqib Mehmood, Abbasi Masroor Manshad

机构信息

Dental Section, Abbottabad International Medical College, Abbottabad-Pakistan.

Department of Dentistry, Ayub Medical College, Abbottabad, Pakistan.

出版信息

J Ayub Med Coll Abbottabad. 2018 Oct-Dec;30(4):524-528.

Abstract

BACKGROUND

Alveolar osteitis is a frequent postoperative complication of third molar surgery. A number of preventive methods have been tried. Chlorhexidine is most widely used antiseptic which is thought to be helpful to prevent alveolar osteitis. The objective of this study was to evaluate role of 0.2% bio-adhesive chlorhexidine gel in reducing incidence of alveolar osteitis after surgical removal of mandibular third molars which causes extra monetary burden on the patients in the form of several follow up visits..

METHODS

A randomized clinical trial was performed in the Dental Section, Ayub Medical College, Abbottabad. Approval from ethical committee was obtained. Total 180 patients were randomly divided into Group A in which patients received 0.2% bio-adhesive chlorhexidine gel and Group B where patients received placebo gel in the extraction socket after removal of mandibular third molar.

RESULTS

0.2% bio-adhesive chlorhexidine gel used after mandibular third molar removal reduced incidence of alveolar osteitis by 10% in comparison to control group with statistically significant difference, i.e., p=0.044..

CONCLUSIONS

2.3 times reduction in the incidence of alveolar osteitis was observed after use of 0.2% bio-adhesive chlorhexidine gel.

摘要

背景

牙槽骨炎是第三磨牙手术常见的术后并发症。人们尝试了多种预防方法。洗必泰是最广泛使用的防腐剂,被认为有助于预防牙槽骨炎。本研究的目的是评估0.2%生物黏附性洗必泰凝胶在降低下颌第三磨牙拔除术后牙槽骨炎发生率方面的作用,下颌第三磨牙拔除术会因多次随访给患者带来额外经济负担。

方法

在阿伯塔巴德阿尤布医学院牙科进行了一项随机临床试验。获得了伦理委员会的批准。180例患者被随机分为A组,该组患者在拔除下颌第三磨牙后在拔牙窝内使用0.2%生物黏附性洗必泰凝胶;B组患者在拔牙窝内使用安慰剂凝胶。

结果

下颌第三磨牙拔除后使用0.2%生物黏附性洗必泰凝胶,与对照组相比,牙槽骨炎发生率降低了10%,差异具有统计学意义,即p = 0.044。

结论

使用0.2%生物黏附性洗必泰凝胶后,牙槽骨炎发生率降低了2.3倍。

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