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[格里戈列夫-志贺氏痢疾病原体的全球大流行与耐药性]

[The world-wide pandemic and drug resistance of the causative agent of Grigor'ev-Shiga dysentery].

作者信息

Solodovnikov Iu P, Myl'nikova G S

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1988 Nov(11):56-61.

PMID:3064514
Abstract

One of the factors facilitating the global pandemic of Grigor'ev-Shiga dysentery is considered in detail. All Shigella dysenteriae 1 strains, irrespective of the geographical zone of their spread, showed medicinal resistance. As pandemic developed, the spectrum of medicinal resistance constantly increased in all hyperendemic foci. The presence of pronounced relationships between the strains circulating in each of three hyperendemic foci and the strains circulating in different hyperendemic foci could be observed. The necessity of paying greater attention to this dangerous infectious disease, and especially to the problems related to the medicinal resistance of its causative agents, is emphasized.

摘要

详细探讨了促使格里戈列夫-志贺痢疾在全球大流行的因素之一。所有痢疾志贺氏菌1型菌株,无论其传播的地理区域如何,均表现出耐药性。随着大流行的发展,所有高度流行疫源地的耐药谱不断增加。可以观察到在三个高度流行疫源地中每个疫源地流行的菌株与在不同高度流行疫源地中流行的菌株之间存在明显的关系。强调了必须更加关注这种危险的传染病,特别是与其病原体耐药性相关的问题。

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