Department of Bariatric Surgery, Orlando Regional Medical Center, Orlando Health, 89 Copeland Dr, 1st Floor, Orlando, FL, USA.
Wolverine Anesthesia Consultants Inc, Orlando, FL, USA.
Obes Surg. 2019 Apr;29(4):1099-1104. doi: 10.1007/s11695-018-03668-5.
Postoperative pain remains the most common challenge following inpatient and outpatient surgeries, and, therefore, opioid analgesics are widely used during the perioperative period. The aim of this study is to examine the efficiency of transversus abdominis plane (TAP) block using liposomal bupivacaine in reducing the use of opioid analgesics during the perioperative period of bariatric procedures.
A retrospective chart review was performed on 191 patients who underwent a laparoscopic bariatric procedure between September 13, 2017, and February 26, 2018. A total of 97 patients received TAP block with liposomal bupivacaine, and 94 patients did not receive TAP block.
Baseline patient characteristics were comparable between the two groups. The mean age was 43.7 and 41.1 years, and the mean preoperative body mass index (BMI) was 45.6 and 46.1 kg/m in TAP and non-TAP groups, respectively. In the TAP group, 65 patients (69.2%) received intravenous (IV) hydromorphone or morphine while 93 (95.9%) did in the non-TAP group (p < 0.0001). In the TAP group, 44 (46.8%) received oral opioid analgesic while 73 (75.3%) did in the non-TAP group (p < 0.0001). The odds of receiving IV hydromorphone or morphine for TAP group was about 0.10 times the corresponding odds for non-TAP group, and the odds of receiving oral opioid analgesic for the TAP group was about 0.29 times the corresponding odds for the non-TAP group.
The use of preoperative TAP block with liposomal bupivacaine significantly decreased the use of IV and oral opioid analgesics. A larger prospective study may be needed to further validate the results.
术后疼痛仍然是住院和门诊手术后最常见的挑战,因此,围手术期广泛使用阿片类镇痛药。本研究旨在探讨腹横肌平面(TAP)阻滞联合包载布比卡因脂质体在减少减重手术围手术期阿片类镇痛药使用中的效果。
对 2017 年 9 月 13 日至 2018 年 2 月 26 日期间接受腹腔镜减重手术的 191 例患者进行回顾性图表审查。共 97 例患者接受 TAP 阻滞联合包载布比卡因脂质体,94 例患者未接受 TAP 阻滞。
两组患者的基线特征无差异。TAP 组和非 TAP 组患者的平均年龄分别为 43.7 岁和 41.1 岁,平均术前体重指数(BMI)分别为 45.6kg/m2和 46.1kg/m2。TAP 组 65 例(69.2%)患者接受静脉(IV)氢吗啡酮或吗啡,而非 TAP 组 93 例(95.9%)患者接受(p<0.0001)。TAP 组 44 例(46.8%)患者接受口服阿片类镇痛药,而非 TAP 组 73 例(75.3%)患者接受(p<0.0001)。TAP 组接受 IV 氢吗啡酮或吗啡的可能性约为非 TAP 组的 0.10 倍,接受口服阿片类镇痛药的可能性约为非 TAP 组的 0.29 倍。
术前 TAP 阻滞联合包载布比卡因脂质体可显著减少 IV 和口服阿片类镇痛药的使用。可能需要更大的前瞻性研究来进一步验证结果。