新生儿干细胞库的未来状况

Brown Katherine S, Rao Mahendra S, Brown Heather L

Scientific and Medical Affairs, Cbr Systems Inc., 611 Gateway Blvd, Suite 820, South San Francisco, CA 94080, USA.

Collaborative Science Chair, InSTEM, Bangalore 560065, India.

J Clin Med. 2019 Jan 18;8(1):117. doi: 10.3390/jcm8010117.

Newborn stem cell banking began with the establishment of cord blood banks more than 25 years ago. Over the course of nearly three decades, there has been considerable evolution in the clinical application of stem cells isolated from newborn tissues. The industry now finds itself at an inflection point as personalized medicine and regenerative medicine continue to advance. In this review, we summarize our perspective on newborn stem cell banking in the context of the future potential that stem cells from perinatal tissues are likely to play in nascent applications. Specifically, we describe the relevance of newborn stem cell banking and how the cells stored can be utilized as starting material for the next generation of advanced cellular therapies and personalized medicine.

新生儿干细胞库始于25多年前脐带血库的建立。在近三十年的时间里，从新生儿组织中分离出的干细胞的临床应用有了相当大的发展。随着个性化医疗和再生医学的不断进步，该行业如今正处于一个转折点。在这篇综述中，我们在围产期组织干细胞可能在新兴应用中发挥的未来潜力的背景下，总结了我们对新生儿干细胞库的看法。具体而言，我们描述了新生儿干细胞库的相关性，以及所储存的细胞如何能够用作下一代先进细胞疗法和个性化医疗的起始材料。