斯洛文尼亚一家大型教学医院中的耐甲氧西林金黄色葡萄球菌（MRSA）多样性及牲畜相关耐甲氧西林金黄色葡萄球菌（LA-MRSA）的出现。
MRSA diversity and the emergence of LA-MRSA in a large teaching hospital in Slovenia.
作者信息
Kevorkijan Božena Kotnik, Petrovič Živa, Kocuvan Aleksander, Rupnik Maja
机构信息
1 Department of Infectious Diseases, University Clinical Centre Maribor , Maribor, Slovenia.
2 Centre for Medical Microbiology, National Laboratory for Health, Environment and Food , Maribor, Slovenia.
出版信息
Acta Microbiol Immunol Hung. 2019 Jun 1;66(2):235-246. doi: 10.1556/030.65.2018.052. Epub 2019 Jan 25.
The methicillin-resistant (MRSA) is one of the major causes of a variety of infections in hospitals and the community. One of the most prominent changes in the MRSA epidemiology is the emergence of livestock-associated MRSA (LA-MRSA) strains in the human population. The aim of this study was to follow the MRSA epidemiology in a large teaching hospital during an 8-year time period (2006-2013). Altogether 519 MRSA, cultured from screening or clinical samples, were distributed into 77 types, of which three (t003 and t001, associated with CC5; and t015; associated with CC45) were the most common. LA-MRSA-associated types (t011, t034, t108, t899; associated with CC398) started to emerge in the year 2009 and continued to be found annually at a frequency from 3.9% to 12.7% of all MRSA strains examined. Only 6 of 27 LA-MRSA strains were associated with infections.
耐甲氧西林金黄色葡萄球菌（MRSA）是医院和社区各种感染的主要病因之一。MRSA流行病学最显著的变化之一是人群中出现了与牲畜相关的MRSA（LA-MRSA）菌株。本研究的目的是追踪一家大型教学医院在8年期间（2006 - 2013年）的MRSA流行病学情况。从筛查或临床样本中培养出的519株MRSA共分为77种类型，其中三种（与CC5相关的t003和t001；与CC45相关的t015）最为常见。与LA-MRSA相关的类型（与CC398相关的t011、t034、t108、t899）于2009年开始出现，并在随后每年检测的所有MRSA菌株中以3.9%至12.7%的频率持续被发现。27株LA-MRSA菌株中仅有6株与感染有关。
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