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泪点和泪小管栓子:适应证、疗效与安全性。

Punctal and canalicular plugs: Indications, efficacy and safety.

作者信息

Best A-L, Labetoulle M, Legrand M, M'garrech M, Barreau E, Rousseau A

机构信息

Ophthalmology Service, Hôpital Bicêtre, Assistance publique-Hôpitaux de Paris, Université Paris-Sud, Division of Vision and Disabilities, OPHTARA rare eye disease, 78, rue du Général-Leclerc, 94275 Le Kremlin-Bicêtre cedex, France.

Ophthalmology Service, Hôpital Bicêtre, Assistance publique-Hôpitaux de Paris, Université Paris-Sud, Division of Vision and Disabilities, OPHTARA rare eye disease, 78, rue du Général-Leclerc, 94275 Le Kremlin-Bicêtre cedex, France; Viral and autoimmune disease immunology (IMVA/Infrastructure IDMIT) UMR 1184, CEA, 92260 Fontenay-aux-Roses, France.

出版信息

J Fr Ophtalmol. 2019 Mar;42(3):e95-e104. doi: 10.1016/j.jfo.2018.12.003. Epub 2019 Jan 26.

Abstract

Lacrimal occlusion with punctal or canalicular plugs have been used to treat dry eye disease for more than 40 years. Indeed, punctal plugs constitute a safe and effective tool to retain the natural tear film and prolong the effect of tear substitutes. A wide variety of plugs is available, differing in their design, location (punctal versus canalicular) and their resorbability. There indications have increasingly broadened, and they are now one of the treatment options for numerous ocular surface diseases. Current research focuses on using punctal plugs for extended delivery of drugs to the ocular surface. This review addresses physiology of lacrimal drainage, available models of punctal plugs, their indications, practical details of prescribing and placing punctal and canalicular plugs, and possible complications.

摘要

使用泪点或泪小管塞阻塞泪道治疗干眼疾病已有40多年历史。事实上,泪点塞是保留天然泪膜和延长泪液替代物作用的一种安全有效的工具。有各种各样的泪点塞,其设计、位置(泪点塞与泪小管塞)和可吸收性各不相同。其适应证日益广泛,目前已成为众多眼表疾病的治疗选择之一。当前的研究集中在使用泪点塞将药物延长递送至眼表。本文综述了泪液引流的生理学、现有的泪点塞类型、其适应证、开具处方及放置泪点塞和泪小管塞的实际细节以及可能的并发症。

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