与单纯疱疹病毒及病毒和细菌性人畜共患病相关的抗N-甲基-D-天冬氨酸受体脑炎
Anti-NMDAR Encephalitis in Association with Herpes Simplex Virus and Viral and Bacterial Zoonoses.
作者信息
Yan Hung Stefanie Kar, Hiew Fu Liong, Viswanathan Shanthi
机构信息
Department of Neurology, Kuala Lumpur Hospital, Jalan Pahang, 50586 Kuala Lumpur, Malaysia.
出版信息
Ann Indian Acad Neurol. 2019 Jan-Mar;22(1):102-103. doi: 10.4103/aian.AIAN_232_18.
Abstract
Multiple co-infections can predispose a patient to autoimmune encephalitis. Out of thirty cases of N-methyl-D-aspartate receptor (NMDAR) encephalitis seen at a single tertiary referral center, only two cases of co-infection with NMDAR encephalitis were identified. One of these cases was highly interesting due to the presence of more than one co-infections along with the presence of cortical dysfunction, seizures, and orofacial dyskinesias at the onset in a male in the absence of tumors, which was refractory to initial treatment.
摘要
多重合并感染可使患者易患自身免疫性脑炎。在一家三级转诊中心所见的30例N-甲基-D-天冬氨酸受体（NMDAR）脑炎病例中，仅发现2例合并NMDAR脑炎感染。其中1例非常有趣，因为该男性患者起病时存在不止一种合并感染，同时伴有皮质功能障碍、癫痫发作和口面部运动障碍，且无肿瘤，初始治疗无效。
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