Département de Psychiatrie, Centre Universitaire Hospitalier (CHU) de Montpellier, 34000, Montpellier, France.
Centre de Ressources Autisme Languedoc-Roussillon, CHU Montpellier, 39 Avenue Charles Flahaut, 34295, Montpellier, France.
J Autism Dev Disord. 2019 Jun;49(6):2243-2256. doi: 10.1007/s10803-019-03901-9.
There is limited data on long-term outcome of ASD with co-occurring intellectual disabilities (ID) and challenging behaviours in France. The EpiTED period cohort is a 15 years longitudinal study of the developmental trajectories of 281 children initially recruited at mean age of 5 years. Two contrasted developmental trajectories were identified. Low cognitive level, absence of language, and higher ASD scores at baseline were predictive of low growth at follow-up. As adults the participants were predisposed to persistent co-occurring challenging behaviours as well as underlying ID impacting their ability to function independently. The results underscore the need for development of services and supports for adults with ASD in France who may also have already lacked access to adequate interventions and support services.
法国针对伴有智力障碍(ID)和行为障碍的自闭症患者的长期预后数据有限。EpiTED 队列研究是一项为期 15 年的纵向研究,对 281 名最初在 5 岁时招募的儿童的发育轨迹进行了研究。研究确定了两种截然不同的发育轨迹。低认知水平、无语言以及基线时较高的自闭症评分,预示着随访时的增长较低。作为成年人,参与者容易出现持续存在的行为障碍以及潜在的 ID,这会影响他们独立生活的能力。这些结果强调了法国需要为自闭症成年人开发服务和支持,这些成年人可能已经无法获得足够的干预和支持服务。