调查社区护理环境中成年患者用药错误的流行病学情况。沙特阿拉伯中部的一项回顾性队列研究。
Investigating the epidemiology of medication errors in adults in community care settings. A retrospective cohort study in central Saudi Arabia.
作者信息
Assiri Ghadah A, Alkhenizan Abdullah Hm, Al-Khani Salma A, Grant Liz M, Sheikh Aziz
机构信息
The Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, United Kingdom. E-mail.
出版信息
Saudi Med J. 2019 Feb;40(2):158-167. doi: 10.15537/smj.2019.2.23933.
OBJECTIVES
To investigate the period prevalence and risk factors for clinically important prescription and monitoring errors among adults managed in community care in Saudi Arabia (SA).
METHODS
This retrospective cohort study used electronic health record (HER) data. A random sample comprising of 2,000 adults (≥18 years old) visiting Family Medicine clinics in King Faisal Specialist Hospital and Research Center (KFSH & RC), Riyadh, SA, was selected. Data collection took 3 months (October December 2017). Descriptive analyses and logistic regression modeling were performed using STATA (version 14) statistical software. Results: The overall period prevalence of medication errors over 15 months was 8.1% (95% confidence interval [CI] 6.5-9.7). Risk factors that significantly predicted overall risk of patients experiencing one or more medication errors were: age ≥65 years, male gender, Saudi nationality, and polypharmacy (defined as the concurrent use of ≥5 drugs).
CONCLUSIONS
Clinically important medication errors were commonly observed in relation to both drug prescription and monitoring.
目的
调查沙特阿拉伯（SA）社区护理中成人临床重要处方和监测错误的期间患病率及风险因素。
方法
这项回顾性队列研究使用了电子健康记录（HER）数据。选取了沙特阿拉伯利雅得法赫德国王专科医院及研究中心（KFSH & RC）就诊于家庭医学诊所的2000名成年人（≥18岁）的随机样本。数据收集历时3个月（2017年10月至12月）。使用STATA（版本14）统计软件进行描述性分析和逻辑回归建模。
结果
15个月内用药错误的总体期间患病率为8.1%（95%置信区间[CI] 6.5 - 9.7）。显著预测患者发生一次或多次用药错误总体风险的风险因素为：年龄≥65岁、男性、沙特国籍以及多药联用（定义为同时使用≥5种药物）。
结论
在药物处方和监测方面均普遍观察到临床重要用药错误。
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