Exosomes: fighting cancer with cancer.
作者信息
Alyamani Hanin, Obeid Mohammad A, Tate Rothwelle J, Ferro Valerie A
机构信息
Strathclyde Institute of Pharmacy & Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, G4 0RE Glasgow, United Kingdom.
Department of Pharmaceutical Sciences, Faculty of Pharmacy, Yarmouk University, Shafiq Irshidat Street, 21163, Irbid, Jordan.
出版信息
Ther Deliv. 2019 Jan;10(1):37-61. doi: 10.4155/tde-2018-0051.
Exosomes are nanovesicles secreted by many cells, including cancer cells. Extensive research has been carried out to validate potential applications of exosomes and to evaluate their efficiency in a wide range of diseases, including cancer. The current knowledge on the origin, biogenesis and composition of exosomes is described. This review then focuses on the use of exosomes in cancer diagnostics and therapeutics.
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