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来自泰国一名未患病的蝙蝠粪便采集者的人类冠状病毒HKU1的首个完整基因组序列。

First Complete Genome Sequence of Human Coronavirus HKU1 from a Nonill Bat Guano Miner in Thailand.

作者信息

Joyjinda Yutthana, Rodpan Apaporn, Chartpituck Pongtorn, Suthum Krairerk, Yaemsakul Suphaluk, Cheun-Arom Thaniwan, Bunprakob Saowalak, Olival Kevin J, Stokes Martha M, Hemachudha Thiravat, Wacharapluesadee Supaporn

机构信息

Thai Red Cross Emerging Infectious Disease-Health Science Centre, World Health Organization Collaborating Centre for Research and Training on Viral Zoonoses, Chulalongkorn Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

The 5th Office of Disease Prevention and Control, Ratchaburi, Thailand.

出版信息

Microbiol Resour Announc. 2019 Feb 7;8(6). doi: 10.1128/MRA.01457-18. eCollection 2019 Feb.

DOI:10.1128/MRA.01457-18
PMID:30746519
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6368654/
Abstract

Human coronavirus HKU1 (HCoV-HKU1) was first detected in a patient with viral pneumonia from Hong Kong in 2004. Here, we report the first complete genome sequence of HCoV-HKU1 from Thailand, obtained from a nonill person who worked in a bat cave. Phylogenetic tree analysis revealed it as a group B HCoV-HKU1.

摘要

人类冠状病毒HKU1（HCoV-HKU1）于2004年首次在一名来自香港的病毒性肺炎患者中被检测到。在此，我们报告了来自泰国的HCoV-HKU1的首个完整基因组序列，该序列取自一名在蝙蝠洞工作的未患病人员。系统发育树分析显示它属于B组HCoV-HKU1。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b7d/6368654/404cdb5f3ac4/MRA.01457-18-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b7d/6368654/404cdb5f3ac4/MRA.01457-18-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b7d/6368654/404cdb5f3ac4/MRA.01457-18-f0001.jpg

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