Suppr超能文献

Genetic variant rs17185536 regulates gene expression in human brain hypothalamus.

作者信息

Liu Guiyou, Hu Yang, Han Zhifa, Jin Shuilin, Jiang Qinghua

机构信息

Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.

Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100054, China.

出版信息

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3347-3348. doi: 10.1073/pnas.1821550116. Epub 2019 Feb 12.

Abstract
摘要

相似文献

1
Genetic variant rs17185536 regulates gene expression in human brain hypothalamus.
Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3347-3348. doi: 10.1073/pnas.1821550116. Epub 2019 Feb 12.
2
Some concerns regarding the association of rs17185536 in SIM1 with erectile dysfunction.
Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17631. doi: 10.1073/pnas.1905970116. Epub 2019 Aug 13.
3
Reply to Liu et al.: Tissue specificity of gene expression and erectile dysfunction.
Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3349-3350. doi: 10.1073/pnas.1900162116. Epub 2019 Feb 12.
4
Re: Genetic Variation in the SIM1 Locus is Associated with Erectile Dysfunction.
J Urol. 2019 Jun;201(6):1056. doi: 10.1097/JU.0000000000000215.
5
Genetic variation in the locus is associated with erectile dysfunction.
Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):11018-11023. doi: 10.1073/pnas.1809872115. Epub 2018 Oct 8.
6
GWAS Identifies Risk Locus for Erectile Dysfunction and Implicates Hypothalamic Neurobiology and Diabetes in Etiology.
Am J Hum Genet. 2019 Jan 3;104(1):157-163. doi: 10.1016/j.ajhg.2018.11.004. Epub 2018 Dec 21.
7
Sim1 inhibits bone formation by enhancing the sympathetic tone in male mice.
Endocrinology. 2015 Apr;156(4):1408-15. doi: 10.1210/en.2014-1872. Epub 2015 Jan 21.
8
Copy number variation (CNV) analysis and mutation analysis of the 6q14.1-6q16.3 genes SIM1 and MRAP2 in Prader Willi like patients.
Mol Genet Metab. 2016 Mar;117(3):383-8. doi: 10.1016/j.ymgme.2016.01.003. Epub 2016 Jan 9.
10
Impact of Sim1 gene dosage on the development of the paraventricular and supraoptic nuclei of the hypothalamus.
Eur J Neurosci. 2009 Dec;30(12):2239-49. doi: 10.1111/j.1460-9568.2009.07028.x. Epub 2009 Dec 10.

引用本文的文献

1
ASVBM: Structural variant benchmarking with local joint analysis for multiple callsets.
Comput Struct Biotechnol J. 2025 Jun 29;27:2851-2862. doi: 10.1016/j.csbj.2025.06.045. eCollection 2025.
3
Gene-Based Testing of Interactions Using XGBoost in Genome-Wide Association Studies.
Front Cell Dev Biol. 2021 Dec 16;9:801113. doi: 10.3389/fcell.2021.801113. eCollection 2021.
4
Multiple Laplacian Regularized RBF Neural Network for Assessing Dry Weight of Patients With End-Stage Renal Disease.
Front Physiol. 2021 Dec 13;12:790086. doi: 10.3389/fphys.2021.790086. eCollection 2021.
5
Testing Gene-Gene Interactions Based on a Neighborhood Perspective in Genome-wide Association Studies.
Front Genet. 2021 Dec 8;12:801261. doi: 10.3389/fgene.2021.801261. eCollection 2021.
6
Genomic Variation Prediction: A Summary From Different Views.
Front Cell Dev Biol. 2021 Nov 25;9:795883. doi: 10.3389/fcell.2021.795883. eCollection 2021.
8
Application of Multilayer Network Models in Bioinformatics.
Front Genet. 2021 Mar 31;12:664860. doi: 10.3389/fgene.2021.664860. eCollection 2021.
9
Prediction of Lymph-Node Metastasis in Cancers Using Differentially Expressed mRNA and Non-coding RNA Signatures.
Front Cell Dev Biol. 2021 Feb 11;9:605977. doi: 10.3389/fcell.2021.605977. eCollection 2021.
10
Assessing Dry Weight of Hemodialysis Patients via Sparse Laplacian Regularized RVFL Neural Network with L-Norm.
Biomed Res Int. 2021 Feb 4;2021:6627650. doi: 10.1155/2021/6627650. eCollection 2021.

本文引用的文献

1
Disease status affects the association between rs4813620 and the expression of Alzheimer's disease susceptibility gene .
Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10519-E10520. doi: 10.1073/pnas.1812975115. Epub 2018 Oct 24.
2
Genetic variation in the locus is associated with erectile dysfunction.
Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):11018-11023. doi: 10.1073/pnas.1809872115. Epub 2018 Oct 8.
3
An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome.
Am J Hum Genet. 2018 Aug 2;103(2):232-244. doi: 10.1016/j.ajhg.2018.07.004. Epub 2018 Jul 26.
4
Genetic Variants and Multiple Sclerosis Risk Gene SLC9A9 Expression in Distinct Human Brain Regions.
Mol Neurobiol. 2017 Nov;54(9):6820-6826. doi: 10.1007/s12035-016-0208-5. Epub 2016 Oct 20.
5
Fast and efficient QTL mapper for thousands of molecular phenotypes.
Bioinformatics. 2016 May 15;32(10):1479-85. doi: 10.1093/bioinformatics/btv722. Epub 2015 Dec 26.
6
Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans.
Science. 2015 May 8;348(6235):648-60. doi: 10.1126/science.1262110. Epub 2015 May 7.
7
Atlas of gene expression in the developing kidney at microanatomic resolution.
Dev Cell. 2008 Nov;15(5):781-91. doi: 10.1016/j.devcel.2008.09.007.
8
Adenoviral-mediated modulation of Sim1 expression in the paraventricular nucleus affects food intake.
J Neurosci. 2006 Jun 28;26(26):7116-20. doi: 10.1523/JNEUROSCI.0672-06.2006.
9
Profound obesity associated with a balanced translocation that disrupts the SIM1 gene.
Hum Mol Genet. 2000 Jan 1;9(1):101-8. doi: 10.1093/hmg/9.1.101.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验