Montalto Massimo, Impagnatiello Michele, Nicolazzi Maria Anna, Congedo Maria Teresa, Landolfi Raffaele
Department of Internal Medicine, Gemelli Hospital, Catholic University, Rome, Italy.
Department of Thoracic Surgery, Gemelli Hospital, Catholic University, Rome, Italy.
Eur J Case Rep Intern Med. 2017 Feb 20;4(4):000583. doi: 10.12890/2017_000583. eCollection 2017.
Intralobar pulmonary sequestration is an uncommon congenital lung anomaly which consists of a mass of normal lung tissue not connected to the normal tracheobronchial tree and supplied by an anomalous systemic artery. Carbohydrate antigen 19-9 (CA 19-9) is widely accepted as a tumour marker for biliary, pancreatic and gastrointestinal cancer. However, CA 19-9 may also be increased in patients with benign disease. We describe the case of a 56-year-old woman with intralobar pulmonary sequestration who underwent unnecessary and extensive diagnostic abdominal examinations because of an increase in CA 19-9 serum levels.
Knowledge of pulmonary sequestration causing increased serum CA 19-9 is important for the internist because it can help in the differential diagnosis even with neoplastic disease.Such awareness can also decrease the use of antibiotics.Familiarity with the condition can reduce the number of invasive examinations performed to exclude neoplasms of the gastrointestinal tract.
叶内型肺隔离症是一种罕见的先天性肺异常，由一团与正常气管支气管树不相连且由异常体动脉供血的正常肺组织组成。糖类抗原19-9（CA 19-9）被广泛认为是胆管、胰腺和胃肠道癌的肿瘤标志物。然而，CA 19-9在良性疾病患者中也可能升高。我们描述了一名56岁叶内型肺隔离症女性患者的病例，该患者因血清CA 19-9水平升高接受了不必要的广泛腹部诊断检查。
内科医生了解肺隔离症导致血清CA 19-9升高很重要，因为这有助于鉴别诊断，即使是肿瘤性疾病。这种认识还可以减少抗生素的使用。熟悉这种情况可以减少为排除胃肠道肿瘤而进行的侵入性检查次数。
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