用于检测喹诺酮类药物的光学和电化学传感器及生物传感器。

Optical and Electrochemical Sensors and Biosensors for the Detection of Quinolones.

机构信息

Department of Food Science and Technology, School of Agriculture, Shiraz University, Shiraz 71441-65186, Iran.

Department of Biomedical Devices and Instrumentation, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo 101-0062, Japan.

出版信息

Trends Biotechnol. 2019 Aug;37(8):898-915. doi: 10.1016/j.tibtech.2019.01.004. Epub 2019 Feb 15.

DOI:10.1016/j.tibtech.2019.01.004

PMID:30777309

Abstract

One major concern associated with food safety is related to residual effects of antibiotics that are widely used to treat animals and result in antimicrobial resistance. Among different groups of antibiotic, the use of quinolones in livestock is of major concern due to the significance of these antimicrobial drugs for the treatment of a range of infectious diseases in humans. Therefore, it is desirable to develop reliable methods for the rapid, sensitive, and on-site detection of quinolone residue levels in animal-derived foods to ensure food safety. Sensors and biosensors are promising future platforms for rapid and on-site monitoring of antibiotic residues. In this review, we focus on recent advancements and modern approaches in quinolone sensors and biosensors.

摘要

食品安全方面的一个主要关注点与抗生素的残留效应有关，这些抗生素被广泛用于治疗动物，并导致抗药性。在不同类别的抗生素中，由于喹诺酮类药物在人类治疗一系列传染病方面的重要性，因此在牲畜中使用喹诺酮类药物引起了极大的关注。因此，开发可靠的方法来快速、灵敏、现场检测动物源性食品中的喹诺酮类残留水平以确保食品安全是非常必要的。传感器和生物传感器是快速现场监测抗生素残留的有前途的未来平台。在这篇综述中，我们重点介绍了喹诺酮传感器和生物传感器的最新进展和现代方法。