Department of Translational Medical Science - Pediatric Section, University of Naples "Federico II", Naples, Italy.
Department of Translational Medical Science - Pediatric Section, University of Naples "Federico II", Naples, Italy,
Ann Nutr Metab. 2018;73 Suppl 4:30-37. doi: 10.1159/000493669. Epub 2019 Feb 19.
Lactose intolerance primarily refers to a syndrome having different symptoms upon the consumption of foods containing lactose. It is one of the most common form of food intolerance and occurs when lactase activity is reduced in the brush border of the small bowel mucosa. Individuals may be lactose intolerant to varying degrees, depending on the severity of these symptoms. When lactose is not digested, it can be fermented by gut microbiota leading to symptoms of lactose intolerance that include abdominal pain, bloating, flatulence, and diarrhea with a considerable intraindividual and interindividual variability in the severity of clinical manifestations. These gastrointestinal symptoms could be similar to cow's milk allergy and could be wrongly labeled as symptoms of "milk allergy." There are important differences between lactose intolerance and cow's milk allergy; therefore, a better knowledge of these differences could limit misunderstandings in the diagnostic approach and in the management of these conditions.
乳糖不耐受主要是指在食用含有乳糖的食物后出现不同症状的综合征。它是最常见的食物不耐受形式之一,发生在小肠黏膜刷状缘乳糖酶活性降低时。个体乳糖不耐受的程度可能不同,这取决于这些症状的严重程度。当乳糖未被消化时,它可以被肠道微生物群发酵,导致乳糖不耐受的症状,包括腹痛、腹胀、气胀和腹泻,其临床表现的严重程度在个体内和个体间具有相当大的可变性。这些胃肠道症状可能与牛奶过敏相似,可能被错误地标记为“牛奶过敏”的症状。乳糖不耐受和牛奶过敏之间存在重要差异;因此,更好地了解这些差异可以减少在诊断方法和这些疾病的管理中出现的误解。