Qureshi Mohammed, Gammoh Emily, Shakil Jawairia, Robbins Richard
HOUSTON METHODIST HOSPITAL, HOUSTON, TEXAS.
Methodist Debakey Cardiovasc J. 2018 Oct-Dec;14(4):273-280. doi: 10.14797/mdcj-14-4-273.
The management of type 2 diabetes mellitus has evolved over the last several years as new antidiabetic agents continue to arrive and change the goals of diabetes care. In 2008, the U.S. Food and Drug Administration mandated that all new antidiabetic agents must demonstrate cardiovascular (CV) safety, which has led to a series of CV outcome trials. In this article, we review the key findings from these CV outcome trials and their impact on diabetes care guidelines.
在过去几年中,随着新型抗糖尿病药物不断问世并改变糖尿病治疗目标,2型糖尿病的管理也在不断演变。2008年,美国食品药品监督管理局规定,所有新型抗糖尿病药物必须证明其心血管(CV)安全性,这引发了一系列心血管结局试验。在本文中,我们回顾了这些心血管结局试验的主要发现及其对糖尿病治疗指南的影响。