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快速非体外循环冠状动脉搭桥术:单中心经验

Fast-track off-pump coronary artery bypass: single-center experience.

作者信息

Mangukia Chirantan, Kachhadia Mehul, Meswani Manish

机构信息

NM Virani Wockhardt Hospitals, Rajkot, Gujarat, India.

出版信息

Asian Cardiovasc Thorac Ann. 2019 May;27(4):256-264. doi: 10.1177/0218492319833266. Epub 2019 Feb 24.

Abstract

AIM

The primary goal of the study was to perform retrospective analysis of fast-track coronary artery bypass grafting at our institute to identify risk factors for prolonged hospital stay. A secondary goal was to identify and compare survival statistics with those published in literature.

METHOD

We performed a retrospective analysis of patients enrolled in our fast-track coronary artery bypass protocol. There were 709 patients with a mean age of 58.85 ± 8.9 years; 572 were men. The mean EuroSCORE II was 2.02% ± 2.64%. Of these 709 patients, 538 (76%) met the requirements for discharge within 100 hours.

RESULTS

Prolonged ventilation or reintubation, major pulmonary complications, gastrointestinal and neurological complications were the strongest predictors of fast-track failure. Persistent atrial fibrillation, postoperative transient renal impairment, requirement for noninvasive ventilation > 3 times, sternal wound infection, insulin-dependent diabetes mellitus, preoperative intraaortic balloon pump for chest pain or ST changes, preoperative severe left ventricular dysfunction, preoperative severe renal impairment, and peripheral arterial disease were also found to be significant risk factors for fast-track failure. Cumulative survival at 66 months of follow-up was 90.2% ± 0.02%.

CONCLUSION

The risk factors listed above were associated with fast-track failure. Smoking cessation helps to nullify the factor of chronic obstructive pulmonary disease. Intraoperative elective insertion of a balloon pump does not affect the fast-track protocol. Survival was comparable to that described in the literature.

摘要

目的

本研究的主要目标是对我院的快速冠状动脉旁路移植术进行回顾性分析,以确定延长住院时间的危险因素。次要目标是识别并将生存统计数据与文献中发表的数据进行比较。

方法

我们对纳入快速冠状动脉旁路移植方案的患者进行了回顾性分析。共有709例患者,平均年龄为58.85±8.9岁;其中572例为男性。欧洲心脏手术风险评估系统(EuroSCORE)II的平均值为2.02%±2.64%。在这709例患者中,538例(76%)符合100小时内出院的要求。

结果

长时间通气或再次插管、严重肺部并发症、胃肠道和神经系统并发症是快速康复失败的最强预测因素。持续性房颤、术后短暂性肾功能损害、无创通气需求>3次、胸骨伤口感染、胰岛素依赖型糖尿病、术前因胸痛或ST段改变使用主动脉内球囊泵、术前严重左心室功能障碍、术前严重肾功能损害以及外周动脉疾病也被发现是快速康复失败的重要危险因素。随访66个月时的累积生存率为90.2%±0.02%。

结论

上述危险因素与快速康复失败相关。戒烟有助于消除慢性阻塞性肺疾病这一因素。术中选择性插入球囊泵不影响快速康复方案。生存率与文献中描述的相当。

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