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口腔黏膜下纤维化的习惯史:我们是否过度强调了?

Habit History in Oral Submucous Fibrosis: Have We Over Emphasized?

作者信息

R Sheshaprasad, Pai Anuradha, Yaji Anisha

机构信息

Department of Oral Medicine and Radiolog , The Oxford dental College, Bengaluru, India. Email:

出版信息

Asian Pac J Cancer Prev. 2019 Feb 26;20(2):451-455. doi: 10.31557/APJCP.2019.20.2.451.

Abstract

Aim: Correlation of habit duration and frequency with clinical grading and histopathologic grouping of oral submucous fibrosis (OSMF). Materials and methods: 48 patients with OSMF were included in the study. Detailed history of each patient, clinical profile and habit history were recorded. Biopsy was performed for histopathological correlation. All the findings were correlated with Kerr et al and Khanna and Andrade classification. Statistical Analysis: Kruskal-wallis test was performed to assess the correlation between the study findings. Results: Out of 48 OSMF cases majority were males. Maximum cases were in clinically and histopathologically respectively. Mouth opening was directly proportional with histopathological grouping as per Khanna et al. No correlation between frequency and habit duration with respect to different stages or severity of the OSMF was noted. Conclusion: Disease staging of OSMF clinically and histopathologically is not directly impacted by habit duration and frequency. Rather than habit centered history and management accordingly, more focus should be given to genetics and susceptibility of patient for OSMF development and progression.

摘要

目的

口腔黏膜下纤维化(OSMF)的习惯持续时间和频率与临床分级及组织病理学分组的相关性。材料与方法:本研究纳入48例OSMF患者。记录每位患者的详细病史、临床特征和习惯史。进行活检以进行组织病理学相关性分析。所有结果均与克尔等人以及坎纳和安德拉德的分类法相关。统计分析:采用克鲁斯卡尔 - 沃利斯检验来评估研究结果之间的相关性。结果:48例OSMF病例中男性居多。分别在临床和组织病理学方面病例数最多。根据坎纳等人的研究,开口度与组织病理学分组成正比。未发现OSMF不同阶段或严重程度的频率与习惯持续时间之间存在相关性。结论:OSMF的临床和组织病理学疾病分期不受习惯持续时间和频率的直接影响。对于OSMF的发展和进展,不应以习惯为中心进行病史记录和相应管理,而应更多地关注患者的遗传因素和易感性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42d7/6897006/020652a974b2/APJCP-20-451-g001.jpg

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