Lemoine Caroline, Keswani Mahima, Superina Riccardo
Division of Transplant Surgery, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medecine, Chicago, IL, USA.
Division of Kidney Diseases, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medecine, Chicago, IL, USA.
J Pediatr Surg. 2019 May;54(5):1069-1075. doi: 10.1016/j.jpedsurg.2019.01.042. Epub 2019 Feb 5.
Peritoneal dialysis (PD) catheter obstruction often leads to surgical revision and may require transition to hemodialysis. The purpose of this study was to evaluate risk factors (including omentectomy) associated with early PD catheter obstruction (<6 months from insertion).
A retrospective review of all PD catheters inserted at a single high-volume referral center (2005-2018) was performed. 185 PD catheters were placed in 123 patients (45 female). Potential risk factors for early catheter obstruction were analyzed using Chi-square analysis (p < 0.05 considered statistically significant).
Median age at catheter insertion was 3.42 years (3 days-39 years). Early catheter obstruction occurred in 42 cases (22.7%). Median time to early obstruction was 24 days (3-118 days). Previous PD catheter placement (p = 0.9) or prior abdominal surgery (p = 0.89) was not associated with obstruction. Weight ≥ 10 kg (p = 0.011) and age ≥ 1 year (p = 0.048) were associated with a significantly higher incidence of obstruction. Overall, omentectomy was associated with a trend in reduction of early obstruction in patients with weight ≥ 10 kg (p = 0.08) and significantly in patients ≥1 year (p = 0.028).
Early PD catheter obstruction appears to occur more often in older patients with a higher weight. Concomitant omentectomy seems beneficial at reducing early catheter obstruction events in those patients.
Retrospective comparative study.
III.
腹膜透析(PD)导管梗阻常导致手术修复,且可能需要转为血液透析。本研究的目的是评估与早期PD导管梗阻(插入后<6个月)相关的危险因素(包括网膜切除术)。
对一家大型转诊中心(2005 - 2018年)插入的所有PD导管进行回顾性研究。123例患者(45例女性)共置入185根PD导管。采用卡方分析对早期导管梗阻的潜在危险因素进行分析(p<0.05认为具有统计学意义)。
导管插入时的中位年龄为3.42岁(3天至39岁)。42例(22.7%)发生早期导管梗阻。早期梗阻的中位时间为24天(3 - 118天)。既往PD导管置入史(p = 0.9)或既往腹部手术史(p = 0.89)与梗阻无关。体重≥10 kg(p = 0.011)和年龄≥1岁(p = 0.048)与梗阻发生率显著升高相关。总体而言,网膜切除术对于体重≥10 kg的患者早期梗阻有降低趋势(p = 0.08),对于≥1岁的患者则有显著降低作用(p = 0.028)。
早期PD导管梗阻似乎在体重较大的老年患者中更常发生。对于这些患者,同时进行网膜切除术似乎有利于减少早期导管梗阻事件。
回顾性比较研究。
III级。