磷腈碱tBu-P4催化的（杂）芳烃上的甲氧基-烷氧基交换反应
Phosphazene Base tBu-P4 Catalyzed Methoxy-Alkoxy Exchange Reaction on (Hetero)Arenes.
作者信息
Shigeno Masanori, Hayashi Kazutoshi, Nozawa-Kumada Kanako, Kondo Yoshinori
机构信息
Department of Biophysical Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Sendai, 980-8578, Japan.
出版信息
Chemistry. 2019 Apr 26;25(24):6077-6081. doi: 10.1002/chem.201900498. Epub 2019 Mar 19.
The organic superbase tBu-P4 catalyzes methoxy-alkoxy exchange reactions on (hetero)arenes with alcohols. The catalytic reaction proceeded efficiently with electron-deficient methoxy(hetero)arenes as well as with a variety of alcohols, including 3-amino-1-propanol, β-citronellol, menthol, and cholesterol. An intramolecular version of this reaction furnished six- and seven-membered ring compounds.
有机超强碱tBu-P4催化（杂）芳烃与醇之间的甲氧基-烷氧基交换反应。该催化反应能有效地与缺电子的甲氧基（杂）芳烃以及多种醇发生反应，这些醇包括3-氨基-1-丙醇、β-香茅醇、薄荷醇和胆固醇。该反应的分子内形式可生成六元环和七元环化合物。
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