Garg Gaurav, Bansal Nupur, Singh Manmeet, Sankhwar Satya Narayan
Department of Urology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Department of Radiotherapy, King George's Medical University, Lucknow, Uttar Pradesh, India.
Indian J Palliat Care. 2019 Jan-Mar;25(1):53-56. doi: 10.4103/IJPC.IJPC_102_18.
To evaluate the role of percutaneous nephrostomy (PCN) in patients of carcinoma bladder presenting with obstructive uropathy.
We evaluated medical records of 33 patients of bladder cancer with obstructive uropathy that presented to a tertiary care hospital in north India from January 2015 to December 2016. Outcome measures included technical success rates, change in blood urea and serum creatinine (measured on Day 1, 7, and 14); and complications of PCN according to Society of Interventional Radiology Guidelines for Percutaneous Nephrostomy.
PCN was done in 30 patients. The mean age of patients was 51 years (range 42-67). 24 patients were male and 6 patients were female. The technical success rates for PCN placement were 93.33%. In 12 patients there was no improvement after PCN insertion. Improvement in clinical condition/kidney function occurred in 18 patients. Out of these 6 patients underwent radical cystectomy with ileal conduit formation and palliative radiotherapy/chemotherapy was given to 5 cases. In the remaining 7 patients, after an initial improvement that lasted for 2 weeks after PCN progressive renal dysfunction developed due to malignancy. Minor complications of PCN were seen in 16.6% of patients and major complications were seen in 10 % of cases.
In selected patients with bladder carcinoma with obstructive uropathy, PCN insertion may improve kidney function tests to normal levels and enable them to receive tumor-specific curative/palliative treatment.
评估经皮肾造瘘术(PCN)在患有梗阻性尿路病的膀胱癌患者中的作用。
我们评估了2015年1月至2016年12月期间在印度北部一家三级护理医院就诊的33例患有梗阻性尿路病的膀胱癌患者的病历。观察指标包括技术成功率、血尿素和血清肌酐的变化(在第1天、第7天和第14天测量);以及根据介入放射学会经皮肾造瘘术指南评估的PCN并发症。
30例患者接受了PCN。患者的平均年龄为51岁(范围42 - 67岁)。男性24例,女性6例。PCN置管的技术成功率为93.33%。12例患者在PCN插入后无改善。18例患者的临床状况/肾功能有所改善。其中6例患者接受了根治性膀胱切除术并形成回肠导管,5例患者接受了姑息性放疗/化疗。其余7例患者在PCN后最初改善持续2周后,因恶性肿瘤出现进行性肾功能不全。16.6%的患者出现了PCN的轻微并发症,10%的病例出现了严重并发症。
在选定的患有梗阻性尿路病的膀胱癌患者中,插入PCN可能将肾功能检查改善至正常水平,并使他们能够接受针对肿瘤的治愈性/姑息性治疗。