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孕期的艾滋病病毒:识别分娩期及围产期艾滋病病毒暴露情况。

HIV in pregnancy: Identification of intrapartum and perinatal HIV exposures.

作者信息

Moore Dorothy L, Allen Upton D

机构信息

Canadian Paediatric Society, Infectious Diseases and Immunization Committee, Ottawa, Ontario.

出版信息

Paediatr Child Health. 2019 Feb;24(1):42-49. doi: 10.1093/pch/pxy181. Epub 2019 Feb 15.

Abstract

The benefits of human immunodeficiency virus (HIV) testing in pregnancy, when combined with appropriate maternal antiretroviral therapy and intrapartum and postnatal prophylaxis, are well established. The vertical rate of transmission of HIV in North America is now well below 2%. Efforts must continue to ensure that these benefits are sustained. Women who have received little or no prenatal care and those who present for delivery with unknown HIV status need immediate testing. As more infants are exposed to antiretroviral agents, strategies need to be implemented to ensure adequate follow-up of these infants. Issues relating to the identification of HIV-exposed infants are highlighted.

摘要

妊娠期间进行人类免疫缺陷病毒(HIV)检测,若结合适当的孕产妇抗逆转录病毒治疗以及分娩期和产后预防措施,其益处已得到充分证实。目前,北美地区HIV的垂直传播率远低于2%。必须继续努力以确保维持这些益处。几乎未接受或未接受产前护理的妇女以及分娩时HIV感染状况不明的妇女需要立即进行检测。随着越来越多的婴儿接触抗逆转录病毒药物,需要实施相应策略以确保对这些婴儿进行充分的随访。文中突出了与识别HIV暴露婴儿相关的问题。

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