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[疥疮]

[Scabies].

作者信息

Bernigaud Charlotte, Chosidow Olivier

机构信息

Service de dermatologie, AP-HP, hôpital Henri-Mondor, université Paris-Est, Créteil, France.

Dynamyc, EA7380, université Paris-Est, EnvA, Maisons-Alfort et Créteil, France.

出版信息

Rev Prat. 2018 Jan;68(1):63-69.

Abstract

Scabies. Scabies is a parasitic skin disease specific to humans caused by a microscopic mite, Sarcoptes scabiei var. hominis. Scabies is a common contagious disease, with a prevalence that is likely to be on rise, causing an important public health burden worldwide. Scabies is often considered as a benign disease, but its morbidity is actually overlooked and probably underestimated, especially in tropical countries. Scabies morbidity is mainly caused by associated bacterial infections. Scabies is transmitted from one person to another by direct and prolonged skin-to-skin contact. Less often, scabies can be transmitted by indirect contact, for example with contaminated clothes. The main risk factors for transmission of the disease are close contacts, overcrowding within household, communities, but also nursing homes or institutions. Therapeutic management can be challenging and requires time in consultation. Good understanding and compliance of patients are essential for a successful treatment. The therapeutic arsenal mainly comprises molecules for topical use. Ivermectin is the only oral drug available. None of the treatments currently available have sufficient ovicidal activity. This dictates to systematically suggesting two applications/ doses for the patient, as well for the contact subjects.

摘要

疥疮。疥疮是一种由微小螨虫人疥螨(Sarcoptes scabiei var. hominis)引起的人类特异性寄生虫皮肤病。疥疮是一种常见的传染病,其患病率可能呈上升趋势,在全球范围内造成了重大的公共卫生负担。疥疮通常被认为是一种良性疾病,但其发病率实际上被忽视且可能被低估了,尤其是在热带国家。疥疮的发病主要由相关细菌感染引起。疥疮通过直接和长时间的皮肤接触在人与人之间传播。较少情况下,疥疮可通过间接接触传播,例如接触被污染的衣物。该疾病传播的主要风险因素包括密切接触、家庭、社区内人员过度拥挤,以及养老院或机构等场所。治疗管理可能具有挑战性,需要花费时间进行咨询。患者的良好理解和依从性对于成功治疗至关重要。治疗药物主要包括外用药物。伊维菌素是唯一可用的口服药物。目前可用的治疗方法均没有足够的杀卵活性。这就要求必须为患者以及接触者系统性地建议进行两次用药/剂量治疗。

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