Samian C, Ghaffar S, Nandapalan V, Santosh S
Department of Otorhinolaryngology and Head and Neck Surgery, St Helens and Knowsley NHS Teaching Hospitals , Whiston, Merseyside , UK.
Department of Pathology, St Helens and Knowsley NHS Teaching Hospitals , Whiston, Merseyside , UK.
Ann R Coll Surg Engl. 2019 May;101(5):309-312. doi: 10.1308/rcsann.2019.0024. Epub 2019 Mar 11.
Malakoplakia is a rare chronic inflammatory disorder, predominantly affecting the urinary tract. In the head and neck region, it is very rare and may confuse the clinicians during investigations, as features may mimic malignancy.
We report a case of malakoplakia involving the parotid gland and review of the reported cases of malakoplakia in head and neck region.
Histologically, this is the first classic case report of malakoplakia involving the parotid gland in the world literature. A total of 49 cases have been reported in the head and neck region; 38.7% of these are cutaneous. In soft tissue, the tongue is the most common site. Salivary gland involvement is very rare. Previously, submandibular salivary gland involvement has been reported.
A possibility of malakoplakia should be considered as a differential diagnosis in patients with enlarged head and neck masses. Histology is essential to diagnose this benign inflammatory disorder and to differentiate from a malignant process.
软斑病是一种罕见的慢性炎症性疾病,主要影响泌尿系统。在头颈部区域,它非常罕见,在检查过程中可能会使临床医生感到困惑,因为其特征可能类似恶性肿瘤。
我们报告一例累及腮腺的软斑病病例,并回顾头颈部区域已报道的软斑病病例。
从组织学角度来看,这是世界文献中首例累及腮腺的经典软斑病病例报告。头颈部区域共报道了49例;其中38.7%为皮肤型。在软组织中,舌头是最常见的部位。唾液腺受累非常罕见。此前曾有下颌下唾液腺受累的报道。
对于头颈部肿块增大的患者,应考虑软斑病作为鉴别诊断的可能性。组织学检查对于诊断这种良性炎症性疾病并与恶性病变相鉴别至关重要。