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本文引用的文献

1
Notes from the Field: Use of Electronic Cigarettes and Any Tobacco Product Among Middle and High School Students - United States, 2011-2018.实地记录:2011 - 2018年美国初高中学生使用电子烟及其他烟草制品的情况
MMWR Morb Mortal Wkly Rep. 2018 Nov 16;67(45):1276-1277. doi: 10.15585/mmwr.mm6745a5.
2
Inflammatory and Oxidative Responses Induced by Exposure to Commonly Used e-Cigarette Flavoring Chemicals and Flavored e-Liquids without Nicotine.接触常用的不含尼古丁的电子烟调味化学品和调味电子烟液所引发的炎症和氧化反应。
Front Physiol. 2018 Jan 11;8:1130. doi: 10.3389/fphys.2017.01130. eCollection 2017.
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Preferring more e-cigarette flavors is associated with e-cigarette use frequency among adolescents but not adults.偏好更多电子烟口味与青少年而非成年人的电子烟使用频率相关。
PLoS One. 2018 Jan 4;13(1):e0189015. doi: 10.1371/journal.pone.0189015. eCollection 2018.
4
Menthol cigarettes and the public health standard: a systematic review.薄荷醇香烟与公众健康标准:系统评价。
BMC Public Health. 2017 Dec 29;17(1):983. doi: 10.1186/s12889-017-4987-z.
5
E-Cigarette Use Causes a Unique Innate Immune Response in the Lung, Involving Increased Neutrophilic Activation and Altered Mucin Secretion.电子烟使用在肺部引起独特的先天免疫反应,涉及中性粒细胞激活增加和粘蛋白分泌改变。
Am J Respir Crit Care Med. 2018 Feb 15;197(4):492-501. doi: 10.1164/rccm.201708-1590OC.
6
E-cigarette use and associated changes in population smoking cessation: evidence from US current population surveys.电子烟使用与人群戒烟的相关变化:来自美国当前人口调查的证据
BMJ. 2017 Jul 26;358:j3262. doi: 10.1136/bmj.j3262.
7
Flavored e-cigarette liquids and cinnamaldehyde impair respiratory innate immune cell function.调味电子烟液和肉桂醛会损害呼吸道固有免疫细胞功能。
Am J Physiol Lung Cell Mol Physiol. 2017 Aug 1;313(2):L278-L292. doi: 10.1152/ajplung.00452.2016. Epub 2017 May 11.
8
A comparative study of electronic cigarette vapor extracts on airway-related cell lines in vitro.电子烟蒸汽提取物对气道相关细胞系的体外比较研究。
Inhal Toxicol. 2017 Feb;29(3):126-136. doi: 10.1080/08958378.2017.1318193.
9
Nicotine, aerosol particles, carbonyls and volatile organic compounds in tobacco- and menthol-flavored e-cigarettes.烟草味和薄荷醇味电子烟中的尼古丁、气溶胶颗粒、羰基化合物和挥发性有机化合物。
Environ Health. 2017 Apr 27;16(1):42. doi: 10.1186/s12940-017-0249-x.
10
Inflammatory Response and Barrier Dysfunction by Different e-Cigarette Flavoring Chemicals Identified by Gas Chromatography-Mass Spectrometry in e-Liquids and e-Vapors on Human Lung Epithelial Cells and Fibroblasts.通过气相色谱-质谱法鉴定电子烟烟液和蒸汽中不同电子烟调味化学品对人肺上皮细胞和成纤维细胞的炎症反应及屏障功能障碍
Appl In Vitro Toxicol. 2017 Mar 1;3(1):28-40. doi: 10.1089/aivt.2016.0030.

青少年、年轻成年人和老年人使用调味电子烟:来自人口评估烟草和健康研究的发现。

Use of Flavored E-Cigarettes Among Adolescents, Young Adults, and Older Adults: Findings From the Population Assessment for Tobacco and Health Study.

机构信息

1 Dartmouth Geisel School of Medicine, Dartmouth-Hitchcock Norris Cotton Cancer Center, Lebanon, NH, USA.

2 Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Geisel School of Medicine, Lebanon, NH, USA.

出版信息

Public Health Rep. 2019 May/Jun;134(3):282-292. doi: 10.1177/0033354919830967. Epub 2019 Mar 12.

DOI:10.1177/0033354919830967
PMID:30857471
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6505324/
Abstract

OBJECTIVES

The use of flavored electronic cigarettes (e-cigarettes) is common among e-cigarette users, but little is known about the potential harms of flavorings, the extent to which the concurrent use of multiple flavor types occurs, and the correlates of flavor type use. The objective of this study was to assess the types of e-cigarette flavors used by adolescent (aged 12-17), young adult (aged 18-24), and older adult (aged ≥25) e-cigarette users.

METHODS

We assessed the prevalence of flavored e-cigarette use within the past month by flavor types and concurrent use of multiple flavor types among past-month e-cigarette users sampled during Wave 2 (2014-2015) of the Population Assessment for Tobacco and Health Study among 414 adolescents, 961 young adults, and 1711 older adults. We used weighted logistic regression models for the use of fruit-, candy-, mint/menthol-, tobacco-, or other-flavored e-cigarettes and concurrent use of multiple flavor types. Covariates included demographic characteristics, e-cigarette use frequency, cigarette smoking status, current use of other tobacco products, and reasons for e-cigarette use.

RESULTS

The leading e-cigarette flavor types among adolescents were fruit, candy, and other flavors; among young adults were fruit, candy, and mint/menthol; and among older adults were tobacco or other flavors, fruit, and mint/menthol. Compared with older adults, adolescents and young adults were more likely to use fruit-flavored e-cigarettes (adjusted odds ratio [aOR] = 3.35; 95% confidence interval [CI], 2.56-4.38; and aOR = 2.31; 95% CI, 1.77-3.01, respectively) and candy-flavored e-cigarettes (aOR = 3.81; 95% CI, 2.74-5.28; and aOR = 2.95; 95% CI, 2.29-3.80, respectively) and concurrently use multiple flavor types (aOR = 4.58; 95% CI, 3.39-6.17; and aOR = 2.28; 95% CI, 1.78-2.91, respectively).

CONCLUSIONS

Regulation of sweet e-cigarette flavors (eg, fruit and candy) may help reduce the use of e-cigarettes among young persons without substantially burdening adult e-cigarette users.

摘要

目的

调味电子烟(e-cigarette)在电子烟使用者中很常见,但人们对调味剂的潜在危害、同时使用多种口味的程度以及口味使用的相关因素知之甚少。本研究的目的是评估青少年(12-17 岁)、年轻成年人(18-24 岁)和老年成年人(≥25 岁)电子烟使用者使用的电子烟口味类型。

方法

我们评估了在 2014-2015 年期间进行的人口评估烟草和健康研究第二波(Wave 2)中,过去一个月内使用过电子烟的青少年(414 人)、年轻成年人(961 人)和老年成年人(1711 人)中,按口味类型评估过去一个月内使用调味电子烟的流行程度,以及同时使用多种口味类型的情况。我们使用加权逻辑回归模型评估水果味、糖果味、薄荷/薄荷醇味、烟草味或其他口味的电子烟以及同时使用多种口味类型的情况。协变量包括人口统计学特征、电子烟使用频率、吸烟状况、当前使用其他烟草制品以及使用电子烟的原因。

结果

青少年中最受欢迎的电子烟口味是水果、糖果和其他口味;年轻成年人中最受欢迎的是水果、糖果和薄荷/薄荷醇口味;而在老年成年人中则是烟草或其他口味、水果和薄荷/薄荷醇口味。与老年成年人相比,青少年和年轻成年人更有可能使用水果味电子烟(调整后的优势比[aOR] = 3.35;95%置信区间[CI],2.56-4.38;aOR = 2.31;95% CI,1.77-3.01)和糖果味电子烟(aOR = 3.81;95% CI,2.74-5.28;aOR = 2.95;95% CI,2.29-3.80),并且同时使用多种口味类型(aOR = 4.58;95% CI,3.39-6.17;aOR = 2.28;95% CI,1.78-2.91)。

结论

对甜味电子烟口味(如水果和糖果味)的监管可能有助于减少年轻人使用电子烟的情况,而不会对成年电子烟使用者造成实质性负担。