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约瑟夫·斯大林究竟死于何种病因?对其疾病、死亡和尸检结果的再评估。

What did Joseph Stalin really die of? A reappraisal of his illness, death, and autopsy findings.

机构信息

Department of Pathology, The Ohio State University, Columbus, OH 43210.

Department of Pathology, The Ohio State University, Columbus, OH 43210.

出版信息

Cardiovasc Pathol. 2019 May-Jun;40:55-58. doi: 10.1016/j.carpath.2019.02.003. Epub 2019 Feb 20.

Abstract

Joseph Stalin was one of the most important world leaders during the first half of the 20th century. He died suddenly in early March 1953 after a short illness, which was described in a series of medical bulletins in the Soviet newspaper Pravda. Based on both the clinical history and autopsy findings, it was concluded that Stalin had died of a massive hemorrhagic stroke involving his left cerebral hemisphere. However, almost 50 years later, a counter-narrative developed suggesting a more nefarious explanation for his sudden death, namely, that a "poison," warfarin, a potent anticoagulant, had been administered surreptitiously by one or more of his close associates during the early morning hours prior to the onset of his stroke. In the present report, we will examine this counter-narrative and suggest that his death was not due to the administration of warfarin but rather to a hypertension-related cerebrovascular accident resulting in a massive hemorrhagic stroke involving his left cerebral hemisphere. The counter-narrative was based on the misunderstanding of certain specific autopsy findings, namely, the presence of focal myocardial and petechial hemorrhages in the gastric and intestinal mucosa, which could be attributed to the extracranial pathophysiologic changes that can occur as a consequence of a stroke rather than the highly speculative counter-narrative that Stalin was "poisoned" by the administration of warfarin.

摘要

约瑟夫·斯大林是 20 世纪上半叶最重要的世界领导人之一。他在患病后于 1953 年 3 月初突然去世,苏联报纸《真理报》发布了一系列医疗公报对此进行了描述。根据临床病史和尸检结果,得出的结论是,斯大林死于左大脑半球的大面积出血性中风。然而,近 50 年后,出现了一种相反的说法,认为他的突然死亡有一个更险恶的解释,即他的一个或多个亲密助手在中风发作前的清晨偷偷给他服用了一种名为华法林的“毒药”,这是一种强效抗凝剂。在本报告中,我们将探讨这种相反的说法,并提出他的死亡不是由于华法林的施用,而是由于与高血压相关的脑血管意外导致的左大脑半球的大面积出血性中风。这种相反的说法是基于对某些特定尸检结果的误解,即胃和肠黏膜存在局灶性心肌和瘀点出血,这可能归因于中风后可能发生的颅外病理生理变化,而不是猜测斯大林被华法林“下毒”的高度推测性的相反说法。

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