Mendoza L, Alfaro A A
Mycopathologia. 1986 May;94(2):123-9. doi: 10.1007/BF00437377.
Thirty-nine pythiosis equine cases, were studied at the Veterinary Medicine School of the National University of Costa Rica, between 1981 and 1984. Lesions were located in different parts of their anatomy: anterior and posterior extremities, abdomen, thorax, breast and mammary gland, and were characterized by their tumoral appearance with necrotic tissue in which yellow-white coral-like necrotic masses, called kunker or leeches were shown. Splendore-Hoeppli like phenomenon and eosinophilic inflammatory reaction around the hyphae, was microscopically observed. Pythium sp. (Hyphomyces destruens) was isolated in Sabouraud dextrose agar from ground kunkers. Immunodiffusion (ID) to diagnose this disease in equines, was performed with success. Immunotherapy was applied to 5 of affected horses, and three were cured. Some epizootiological aspects of the pythiosis are also discussed.
1981年至1984年间,在哥斯达黎加国立大学兽医学院对39例马皮霉病病例进行了研究。病变位于马体解剖结构的不同部位:前后肢、腹部、胸部、乳房和乳腺,其特征为肿瘤样外观,伴有坏死组织,其中可见称做“管型肿”或“水蛭”的黄白色珊瑚状坏死团块。在显微镜下观察到Splendore-Hoeppli样现象及菌丝周围的嗜酸性炎症反应。从磨碎的“管型肿”中,在沙氏葡萄糖琼脂培养基上分离出了腐霉属(毁灭丝菌)。成功地采用免疫扩散法(ID)对马的这种疾病进行诊断。对5匹患病马进行了免疫治疗,其中3匹治愈。还讨论了皮霉病的一些流行病学方面的情况。