Palacios Santiago, González Silvia P, Fernández-Abellán Micaela, Manubens Montserrat, García-Alfaro Pascual
Palacios Institute of Women's Health, Madrid, Spain.
Policlínico HM Gabinete Velázquez, Madrid, Spain.
Sex Med. 2019 Jun;7(2):207-216. doi: 10.1016/j.esxm.2019.01.005. Epub 2019 Mar 16.
The prevalence of menopausal women with confirmed vulvovaginal atrophy (VVA) oscillates between 67-98%.
To assess the prevalence of postmenopausal women with VVA confirmed by gynecologic clinical assessment among all women attending menopause centers in Spain, as well as to describe the impact of VVA on quality of life and sexual functioning.
Women aged 45-75 years old with the last menstrual period >12 months before were included in a cross-sectional study.
Women with ≥1 VVA symptoms filled out a number of questionnaires, including EuroQoL, Day-to-Day Impact of Vaginal Aging, Female Sexual Function Index, and Female Sexual Distress Scale-revised. A gynecologic examination was performed to confirm diagnosis.
1,177 evaluable patients were included. VVA was confirmed in 87.3% of the patients. Almost 80% of women who acknowledged being sexually active (n = 717) presented pain during intercourse. As compared with patients without confirmed VVA (n = 66), patients with confirmed VVA (n = 1,028) were significantly older (P < .0001), had lower rates of sexual activity (P < .05), and used more VVA treatments (P < .05). Severe vaginal atrophy and severe vulvar atrophy were more prevalent in VVA-confirmed women (P < .0001, in both cases). No differences regarding the confirmation of VVA were observed for EuroQoL and Day-to-Day Impact of Vaginal Aging quality-of-life questionnaires. Sexual function measured through the Female Sexual Function Index score was significantly reduced in sexually-active patients with confirmed VVA (P < .05).
VVA signs and symptoms are highly prevalent in Spanish postmenopausal women. Confirmation of VVA diagnosis was associated with impaired sexual function. The early recognition of VVA symptoms should be actively promoted in medical practice, instead of waiting until signs appear to exclude other reasons for VVA and to manage treatment effectively. Palacios S, González SP, Fernández-Abellán M, et al. Impact of Vulvovaginal Atrophy of Menopause in Spanish Women: Prevalence and Symptoms According to the EVES Study. Sex Med 2019;7:207-216.
确诊为外阴阴道萎缩(VVA)的绝经后女性患病率在67%-98%之间波动。
评估在西班牙所有就诊于绝经中心的女性中,经妇科临床评估确诊为VVA的绝经后女性的患病率,并描述VVA对生活质量和性功能的影响。
将年龄在45-75岁且末次月经在12个月以前的女性纳入一项横断面研究。
有≥1种VVA症状的女性填写了一些问卷,包括欧洲五维健康量表、阴道老化的日常影响、女性性功能指数和修订版女性性困扰量表。进行妇科检查以确诊。
纳入了1177例可评估患者。87.3%的患者确诊为VVA。几乎80%承认有性生活的女性(n = 717)在性交时出现疼痛。与未确诊为VVA的患者(n = 66)相比,确诊为VVA的患者(n = 1028)年龄显著更大(P <.0001),性活动率更低(P <.05),且使用VVA治疗的比例更高(P <.05)。严重阴道萎缩和严重外阴萎缩在确诊为VVA的女性中更为普遍(两者均P <.0001)。在欧洲五维健康量表和阴道老化的日常影响生活质量问卷方面,未观察到VVA确诊情况的差异。通过女性性功能指数评分测量的性功能在确诊为VVA的有性生活女性中显著降低(P <.05)。
VVA的体征和症状在西班牙绝经后女性中非常普遍。VVA诊断的确诊与性功能受损有关。在医疗实践中应积极促进对VVA症状的早期识别,而不是等到体征出现才排除VVA的其他原因并有效管理治疗。帕拉西奥斯S、冈萨雷斯SP、费尔南德斯-阿贝兰M等。西班牙女性绝经后外阴阴道萎缩的影响:根据EVES研究的患病率和症状。性医学2019;7:207-216。