Department of adult cardiac surgery, Hopital cardiologique Louis Pradel - LYON medical school, 28, Avenue du Doyen Lépine, 69677 CEDEX, Bron, France.
Université Lyon, INSA-Lyon, LGEF, EA682, F-69621, Villeurbanne, France.
Sci Rep. 2019 Mar 18;9(1):4677. doi: 10.1038/s41598-019-41173-6.
In this paper, we propose a very innovative designed system that enables optimal length adjustment during transapical neochordae implantation for mitral valve repair, increasing accuracy and reproducibility of neochordae length adjustment. Also, such a new device allowed real-time measurement and recording of chordae tension, producing original physiological data. To the best of our knowledge, the tension of chordae had never been measured previously as precisely, especially in in vivo human clinical trials. Preliminary experimental data have been collected on 10 selected patients, giving us the opportunity to assess for the first time the tension applied on the chordae implanted in beating human hearts. The final goal of our measuring device is to provide reliable objective intraoperative data to improve the understanding of changes occurring after mitral valve repair (MVR). This novel measuring instrument may bring change in the paradigm of MVR by allowing repair with strong objective and quantitative, instead of qualitative anatomical analysis.
在本文中,我们提出了一个非常创新的设计系统,该系统可在经心尖植入新腱索时实现最佳长度调整,从而提高腱索长度调整的准确性和可重复性。此外,这种新设备还允许实时测量和记录腱索张力,产生原始的生理数据。据我们所知,以前从未如此精确地测量过腱索的张力,尤其是在体内人体临床试验中。我们已经在 10 名选定的患者身上收集了初步的实验数据,使我们有机会首次评估在跳动的人心内植入的腱索所施加的张力。我们的测量设备的最终目标是提供可靠的术中客观数据,以提高对二尖瓣修复(MVR)后发生的变化的理解。这种新型测量仪器可能会通过允许使用客观的、定量的修复方法来改变 MVR 的范例,而不是使用定性的解剖学分析。