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功能性纳米材料及其在抗菌治疗中的潜在应用

Functional Nanomaterials and Their Potential Applications in Antibacterial Therapy.

作者信息

Hong Le, Luo Shu-Han, Yu Chen-Hao, Xie Yu, Xia Meng-Ying, Chen Ge-Yun, Peng Qiang

机构信息

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

出版信息

Pharm Nanotechnol. 2019;7(2):129-146. doi: 10.2174/2211738507666190320160802.

Abstract

In the past decades, nanomaterials have shown great potential in biomedical fields, especially in drug delivery, imaging and targeted therapy. Recently, the development of novel functional nanomaterials for antibacterial application has attracted much attention. Compared to the traditional direct use of antibiotics, antibacterial nanomaterials either as drug delivery systems or active agents have a higher efficacy and lower side effects. Herein, we will focus on the antibacterial applications of four commonly used nanomaterials, including metal-based nanomaterials, polymeric nanoparticles, graphene oxides or carbon-based nanomaterials and nanogels.

摘要

在过去几十年中,纳米材料在生物医学领域展现出了巨大潜力,尤其是在药物递送、成像和靶向治疗方面。最近,用于抗菌应用的新型功能纳米材料的开发引起了广泛关注。与传统直接使用抗生素相比,作为药物递送系统或活性剂的抗菌纳米材料具有更高的疗效和更低的副作用。在此,我们将重点关注四种常用纳米材料的抗菌应用,包括金属基纳米材料、聚合物纳米颗粒、氧化石墨烯或碳基纳米材料以及纳米凝胶。

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