Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston.
School of Health and Rehabilitation Sciences, The Ohio State University, Columbus.
JAMA Otolaryngol Head Neck Surg. 2019 May 1;145(5):422-430. doi: 10.1001/jamaoto.2019.0055.
Only limited evidence is available describing the contribution of patient-related factors to quality of life in adults with cochlear implants.
Assess the association between demographic, hearing-related, and cochlear implant-related factors and quality of life by using a new Cochlear Implant Quality of Life (CIQOL) item bank, which was developed to meet rigorous psychometric standards.
DESIGN, SETTING, AND PARTICIPANTS: Multicenter cross-sectional study of adults 18 to 89 years of age who had at least 1 year of cochlear implant use and who were recruited through a consortium of 20 cochlear implant centers in the United States. Using an online format, questionnaires were sent to the first 500 participants who contacted the research team. Of these participants, 371 (74.2%) completed the questionnaire. Demographic, hearing-related, and cochlear implant-related data were obtained along with responses to each of the 81 items in the CIQOL item bank. Multivariable linear regression was used to examine demographic, hearing-related, and cochlear implant-related factors associated with scores in each of the 6 CIQOL domains (communication, emotional, entertainment, environment, listening effort, and social).
Association among demographic, hearing-related, and cochlear implant-related factors and CIQOL scores for each of 6 domains.
Of the 371 participants who completed the questionnaire, 222 (59.8%) were women, and the mean (SD) age was 59.5 (14.9) years. The CIQOL scores were normally distributed across the 6 domains. Being employed, having higher household income, longer duration of hearing loss prior to cochlear implantation, and having bilateral rather than unilateral cochlear implantation were associated with higher CIQOL scores in 1 or more domains, but the effect size varied widely (β, 0.1-6.9). Better sentence recognition ability (using AzBio to measure speech recognition) was associated with only a small positive effect size for the communication (β, 0.0 [95% CI, 0.0-0.1]), entertainment (β, 0.0 [95% CI, 0.0-0.1]), and environmental (β, 0.0 [95% CI, 0.0-0.0]) domains. Increased age was associated with lower CIQOL in the entertainment domain (β, -0.3 [95% CI, -1.5 to -0.4]). The demographic, hearing-related, and cochlear implant-related factors included in the multivariable regression models accounted for only a small percentage of the variance in CIQOL domain scores (R2, 0.08-0.17).
Several factors were found to predict higher or lower CIQOL scores in specific domains, with speech-recognition ability having only a minimal association. Despite evaluating a large number of demographic, hearing-related, and cochlear implant-related factors, the multivariable models accounted for only a small amount of CIQOL variance. This suggests that patient or other characteristics that contribute to cochlear implant-related quality of life remain largely unknown.
仅有有限的证据描述了患者相关因素对成人使用人工耳蜗后的生活质量的贡献。
使用新的人工耳蜗生活质量(CIQOL)项目库评估人口统计学、听力相关和人工耳蜗相关因素与生活质量之间的关联,该项目库是为满足严格的心理测量学标准而开发的。
设计、地点和参与者:这是一项在美国 20 个人工耳蜗中心联盟通过合作招募的至少使用人工耳蜗 1 年的 18 至 89 岁成年人的多中心横断面研究。使用在线格式向联系研究小组的前 500 名参与者发送问卷。在这些参与者中,有 371 名(74.2%)完成了问卷。获得了人口统计学、听力相关和人工耳蜗相关的数据,以及人工耳蜗生活质量项目库中 81 个项目中的每个项目的回答。多变量线性回归用于检查与每个 CIQOL 领域(沟通、情感、娱乐、环境、听力努力和社交)中的得分相关的人口统计学、听力相关和人工耳蜗相关因素。
人口统计学、听力相关和人工耳蜗相关因素与每个 6 个 CIQOL 领域的 CIQOL 得分之间的关联。
在完成问卷的 371 名参与者中,有 222 名(59.8%)是女性,平均(SD)年龄为 59.5(14.9)岁。CIQOL 分数在 6 个领域呈正态分布。就业、家庭收入较高、植入人工耳蜗前听力损失时间较长、双侧而非单侧植入人工耳蜗与 1 个或多个领域的 CIQOL 评分较高相关,但效应大小差异很大(β,0.1-6.9)。更好的句子识别能力(使用 AzBio 衡量言语识别)与沟通(β,0.0[95%CI,0.0-0.1])、娱乐(β,0.0[95%CI,0.0-0.1])和环境(β,0.0[95%CI,0.0-0.0])领域的小的正效应大小相关。年龄增长与娱乐领域的 CIQOL 评分降低相关(β,-0.3[95%CI,-1.5 至-0.4])。多变量回归模型中包含的人口统计学、听力相关和人工耳蜗相关因素仅能解释 CIQOL 领域得分的一小部分变异(R2,0.08-0.17)。
发现了一些可以预测特定领域更高或更低 CIQOL 评分的因素,而言语识别能力的相关性极小。尽管评估了大量的人口统计学、听力相关和人工耳蜗相关因素,但多变量模型仅能解释很小比例的 CIQOL 变异。这表明,有助于人工耳蜗相关生活质量的患者或其他特征在很大程度上仍然未知。