Mori Satoshi, Sakurai Kenichi, Fujisaki Shigeru, Kubota Hitomi, Suzuki Yuna, Adachi Keita, Suzuki Shuhei, Tomita Ryouichi
Division of Breast and Endocrine Surgery, Dept. of Surgery, Nihon University School of Medicine.
Gan To Kagaku Ryoho. 2019 Feb;46(2):333-335.
A 75-year-old man noted an elastic hard tumor under his left areola.Mammography showed a microlobulated mass, so he was diagnosed with category Ⅳ breast cancer.Ultrasonography showed a circular hypo-echoic mass that was 21mm in diameter with a moderately indistinct border.Based on core needle biopsy, the tumor was diagnosed as invasive ductal carcinoma.We performed a whole-body check-up, and he was diagnosed with T1N0M0, StageⅠ breast cancer.The patient underwent mastectomy and sentinel lymph node biopsy.The pathological diagnosis based on the resected surgical specimen was invasive ductal carcinoma, positive for ER and negative for PgR and HER2/neu protein expression, and the Ki-67 positive cell index was 20%.The surgical margins were negative, and there was no metastasis in the sentinel lymph nodes.He was administered endocrine therapy as adjuvant therapy.Two years after the surgery, he remains well without metastases.
一名75岁男性发现左乳晕下有一个质地硬且有弹性的肿瘤。乳房X线摄影显示为微叶状肿块,因此他被诊断为Ⅳ期乳腺癌。超声检查显示一个直径21mm的圆形低回声肿块,边界中度不清。基于粗针活检,肿瘤被诊断为浸润性导管癌。我们对他进行了全身检查,诊断为T1N0M0,Ⅰ期乳腺癌。患者接受了乳房切除术和前哨淋巴结活检。根据切除的手术标本进行的病理诊断为浸润性导管癌,雌激素受体(ER)阳性,孕激素受体(PgR)阴性,人表皮生长因子受体2(HER2/neu)蛋白表达阴性,Ki-67阳性细胞指数为20%。手术切缘阴性,前哨淋巴结无转移。他接受了内分泌治疗作为辅助治疗。手术后两年,他状况良好,无转移。