客观性耳鸣的病因、发病机制与治疗：独特病例系列与文献回顾。

The etiology, pathogeneses, and treatment of objective tinnitus: Unique case series and literature review.

机构信息

Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, Yale University School of Medicine, New Haven, CT, United States of America.

出版信息

Am J Otolaryngol. 2019 Jul-Aug;40(4):594-597. doi: 10.1016/j.amjoto.2019.03.017. Epub 2019 Apr 5.

DOI:10.1016/j.amjoto.2019.03.017

PMID:30981445

Abstract

We present two unique cases of myoclonus-induced objective tinnitus (OT), along with a comprehensive literature review on the topic. Primary goals include: explore the relationship between palatal myoclonus (PM) and middle ear myoclonus (MEM), highlight the embryologic, neurologic, and anatomical relationship between the involved peri-tubular muscles, exemplify the first case of OT which documents video evidence demonstrating the link between objective tinnitus and eustachian tube movement. Also, we discuss available treatment interventions and why they often do not fully resolve patients' symptoms. Finally we introduce a novel way to objectively quantify the severity of OT. Ultimately, our series hopes to inform future diagnostic and treatment guidelines.

摘要

我们呈现了两例肌阵挛性客观性耳鸣（OT）的独特病例，并对该主题进行了全面的文献回顾。主要目标包括：探讨腭肌阵挛（PM）和中耳肌阵挛（MEM）之间的关系，强调涉及的管状周围肌肉的胚胎学、神经学和解剖学关系，举例说明 OT 的首例病例，该病例记录了视频证据，证明了客观性耳鸣与咽鼓管运动之间的联系。此外，我们还讨论了现有的治疗干预措施，以及为什么它们通常不能完全解决患者的症状。最后，我们介绍了一种客观量化 OT 严重程度的新方法。最终，我们的系列希望为未来的诊断和治疗指南提供信息。