Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Vanderbilt University Medical Center, 1161 21st Avenue South, B-1100 Medical Center North, Nashville, TN 37232-2519, USA.
Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Thomas Jefferson University, 1020 Walnut Street, Philadelphia, PA 19107, USA.
Clin Perinatol. 2019 Jun;46(2):159-172. doi: 10.1016/j.clp.2019.02.001.
Preterm birth can be medically-indicated or spontaneous. Almost half of spontaneous preterm deliveries are preceded by preterm labor. Preterm labor is a clinical diagnosis characterized by regular uterine contractions (painful or painless) with concomitant cervical change. This article discusses the prevention and treatment of spontaneous preterm labor utilizing progesterone and tocolytic agents and provides management recommendations in patients with and without a history of prior spontaneous preterm birth.
早产可以是医学指征性的,也可以是自发性的。几乎一半的自发性早产之前都有早产临产。早产临产是一种临床诊断,其特征是有规律的子宫收缩(有痛或无痛)伴宫颈变化。本文讨论了使用孕激素和宫缩抑制剂预防和治疗自发性早产,并为有和无既往自发性早产史的患者提供了管理建议。