胎儿颈部半透明厚度：与出生体重及新生儿健康状况是否有关联？
Fetal nuchal translucency: is there an association with birthweight and neonatal wellbeing?
作者信息
Kalem Ziya, Ellibeş Kaya Aşkı, Bakırarar Batuhan, Namlı Kalem Müberra
机构信息
Gürgan Clinic IVF and Women Health Center, Ankara, Turkey.
Düzce University Faculty of Medicine, Department of Obstetrics and Gynecology, Düzce, Turkey.
出版信息
Turk J Obstet Gynecol. 2019 Mar;16(1):35-40. doi: 10.4274/tjod.galenos.2019.21384. Epub 2019 Mar 27.
OBJECTIVE
To evaluate the relationship between nuchal translucency (NT) values with birthweight and the wellbeing of the newborn.
MATERIALS AND METHODS
This retrospective cohort study that included 508 patients made use of data on healthy full-term, singleton, live birth newborns in a university hospital between 2016 and 2018. The relationship between the NT multiple of the median (MoM) value and maternal body mass index, birthweight, sex, need for neonatal intensive care unit (NICU), and APGAR scores was evaluated. Similarly, the relationship between birthweight and NT MoM, and biochemical data in the first trimester was also evaluated.
RESULTS
There was a positive correlation between NT and birthweight (p<0.001). The need for NICU admission increased (p=0.001), and APGAR 1st minute scores decreased (p=0.001) with increasing NT, and APGAR 5th minute scores remained unchanged (p=0.057).
CONCLUSION
The present study identified a positive correlation between first trimester NT and birthweight, and a negative correlation with the wellbeing of the neonate.
目的
评估颈部透明带（NT）值与出生体重及新生儿健康状况之间的关系。
材料与方法
这项回顾性队列研究纳入了508例患者，利用了2016年至2018年期间某大学医院健康足月、单胎、活产新生儿的数据。评估了NT中位数倍数（MoM）值与产妇体重指数、出生体重、性别、新生儿重症监护病房（NICU）需求及阿氏评分之间的关系。同样，也评估了出生体重与NT MoM以及孕早期生化数据之间的关系。
结果
NT与出生体重呈正相关（p<0.001）。随着NT增加，入住NICU的需求增加（p=0.001），阿氏1分钟评分降低（p=0.001），而阿氏5分钟评分保持不变（p=0.057）。
结论
本研究发现孕早期NT与出生体重呈正相关，与新生儿健康状况呈负相关。
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