Department of Surgical, Oncological and Gastrointestinal Sciences, University of Padova, Clinica Chirurgica 3, Padova, Italy.
Laryngoscope. 2020 Mar;130(3):637-640. doi: 10.1002/lary.28030. Epub 2019 Apr 25.
Transoral diverticulostomy/septotomy has become a popular treatment for patients with Zenker diverticulum (ZD). To improve the results of transoral stapler-assisted septotomy, a modification of the technique has been introduced. In this study, we aimed to compare the final outcome of such a modified transoral septotomy (MTS) with the results of traditional transoral septotomy (TTS) in patients with ZD.
Fifty-two consecutive patients with ZD underwent transoral stapler-assisted septotomy between 2010 and 2018. Symptoms were recorded and scored using a detailed questionnaire. Barium swallow, endoscopy, and manometry were performed before and after the procedure.
Of the 52 patients forming the study population (male:female = 35:17), 25 had TTS and 27 had MTS. The patients' demographic and clinical parameters were similar in the two groups. No intraoperative mucosal lesions were detected, and the mortality was nil. The median time taken to complete the procedure was 25 minutes (interquartile range [IQR]: 22-35) for TTS, and 30 minutes (IQR: 25-36) for MTS (P < 0.07). The median follow-up was 69 months (IQR: 46-95) in the TTS group and 30 months (IQR: 25-35) in the MTS group. All patients in both groups had an improvement in their symptom score after the procedure, but the failure rates were 32% (8 of 25) after TTS and 3.7% (1 of 27) after MTS (P < 0.02). At univariate and multivariate analyses, the procedure was the only predictor of a positive final outcome.
Albeit with the intrinsic limitations of the study (retrospective, different time window, and different follow-up), traction on the septum during transoral septotomy improves the final outcome of this treatment in patients with ZD.
4 Laryngoscope, 130:637-640, 2020.
经口内镜下肌切开术/隔切开术已成为Zenker 憩室(ZD)患者的一种流行治疗方法。为了提高经口吻合器辅助隔切开术的效果,引入了该技术的改良。本研究旨在比较改良经口隔切开术(MTS)与传统经口隔切开术(TTS)治疗 ZD 患者的最终结果。
2010 年至 2018 年间,52 例连续 Zenker 憩室患者接受了经口吻合器辅助隔切开术。使用详细问卷记录和评分症状。术前和术后进行钡餐吞咽、内镜和测压检查。
52 例患者形成研究人群(男:女=35:17),25 例行 TTS,27 例行 MTS。两组患者的人口统计学和临床参数相似。术中未发现黏膜损伤,无死亡病例。TTS 组完成手术的中位时间为 25 分钟(四分位距[IQR]:22-35),MTS 组为 30 分钟(IQR:25-36)(P<0.07)。TTS 组的中位随访时间为 69 个月(IQR:46-95),MTS 组为 30 个月(IQR:25-35)。两组患者术后症状评分均有改善,但 TTS 组失败率为 32%(25 例中有 8 例),MTS 组为 3.7%(27 例中有 1 例)(P<0.02)。单因素和多因素分析表明,手术是唯一的阳性结局预测因素。
尽管存在研究的内在局限性(回顾性、不同的时间窗口和不同的随访时间),但在经口隔切开术中对隔进行牵引可改善 ZD 患者的治疗最终结果。
4 级喉镜,130:637-640,2020 年。