我们正在喝掉我们的神经元吗？
Are we drinking our neurones away?
作者信息
Harper C, Kril J, Daly J
出版信息
Br Med J (Clin Res Ed). 1987 Feb 28;294(6571):534-6. doi: 10.1136/bmj.294.6571.534.
Abstract
A quantitative neuropathological necropsy study of the human cerebral cortex showed that the number of cortical neurones in the superior frontal cortex in chronic alcoholic patients is significantly reduced compared with that in controls matched for age and sex. The number of neurones in the motor cortex did not differ significantly between the controls and alcoholics, but in both cortical regions there was evidence that alcoholic patients had smaller (shrunken) neurones than controls. Further studies are necessary to identify other regions of the cerebral cortex that are selectively damaged in brain damage associated with alcohol.
摘要
一项对人类大脑皮质进行的定量神经病理学尸检研究表明，与年龄和性别相匹配的对照组相比，慢性酒精中毒患者额上皮质的皮质神经元数量显著减少。运动皮质中的神经元数量在对照组和酒精中毒患者之间没有显著差异，但在这两个皮质区域都有证据表明，酒精中毒患者的神经元比对照组的更小（萎缩）。有必要进行进一步研究，以确定在与酒精相关的脑损伤中选择性受损的大脑皮质其他区域。
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