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改良全肱骨置换术治疗肱骨罕见骨肉瘤:一例报告

Modified total humeral replacement on unusual osteosarcoma of the humerus: A case report.

作者信息

Prabowo Yogi, Reksoprodjo Adisa Yusuf

机构信息

Department of Orthopaedic & Traumatology, Cipto Mangunkusumo National Central Hospital and Faculty of Medicine, Universitas Indonesia, Jalan Diponegoro No. 71, Central Jakarta, Jakarta 10430, Indonesia.

Department of Orthopaedic & Traumatology, Cipto Mangunkusumo National Central Hospital and Faculty of Medicine, Universitas Indonesia, Jalan Diponegoro No. 71, Central Jakarta, Jakarta 10430, Indonesia.

出版信息

Int J Surg Case Rep. 2019;58:132-137. doi: 10.1016/j.ijscr.2019.04.027. Epub 2019 Apr 17.

Abstract

INTRODUCTION

Osteosarcoma of the humerus is an unusual case. In order to salvage the limb, resection followed with total humeral replacement is preferred. In situations where those prostheses are not available, a technique of modified total humeral replacement could be used.

CASE PRESENTATION

A 20-year-old female patient came with osteosarcoma of the right humerus accompanied by pathological humeral shaft fracture, with the onset of six months. The lesion extended along the proximal to distal part of humerus. The patient underwent a neoadjuvant chemotherapy before surgery and a limb salvage surgery by wide excision of the humerus and reconstruction using modified total humeral replacement was performed. Modifications to the shoulder hemiarthoplasty and total elbow prostheses were made, so both prostheses could join as one unit.

DISCUSSION

After the surgery, no disturbances of hand function were seen, and functional outcome was evaluated by using Musculoskeletal Tumour Society Score (MSTS) score with score of 83% (excellent). After 3 years of follow up, patient could work and resume daily activity with improved MSTS score. There were neither sign of tumor recurrence nor distant metastasis on follow up.

CONCLUSION

Total Humeral Replacement for the treatment of humerus malignancy was feasible by using this modification. This procedure yielded good functional outcome.

摘要

引言

肱骨骨肉瘤是一种罕见病例。为挽救肢体,首选切除后进行全肱骨置换。在无法获得这些假体的情况下,可采用改良全肱骨置换技术。

病例介绍

一名20岁女性患者因右肱骨骨肉瘤伴病理性肱骨干骨折前来就诊,病程6个月。病变沿肱骨近端至远端延伸。患者在手术前接受了新辅助化疗,并通过广泛切除肱骨进行保肢手术,采用改良全肱骨置换进行重建。对半肩关节成形术和全肘关节假体进行了改良,使两个假体能够连接成一个单元。

讨论

术后未见手部功能障碍,采用肌肉骨骼肿瘤学会评分(MSTS)对功能结果进行评估,评分为83%(优秀)。随访3年后,患者能够工作并恢复日常活动,MSTS评分有所提高。随访期间既无肿瘤复发迹象,也无远处转移。

结论

采用这种改良方法进行全肱骨置换治疗肱骨恶性肿瘤是可行的。该手术产生了良好的功能结果。

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